The FbaB‐type fibronectin‐binding protein of Streptococcus pyogenes promotes specific invasion into endothelial cells

Summary Invasive serotype M3 Streptococcus pyogenes are among the most frequently isolated organisms from patients suffering from invasive streptococcal disease and have the potential to invade primary human endothelial cells (EC) via a rapid and efficient mechanism. FbaB protein, the fibronectin‐bi...

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Veröffentlicht in:	Cellular microbiology 2011-08, Vol.13 (8), p.1200-1211
Hauptverfasser:	Amelung, Silva, Nerlich, Andreas, Rohde, Manfred, Spellerberg, Barbara, Cole, Jason N., Nizet, Victor, Chhatwal, Gursharan S., Talay, Susanne R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - genetics Adhesins, Bacterial - metabolism Carrier Proteins - genetics Carrier Proteins - metabolism Cells, Cultured Endocytosis Endothelial cells Endothelial Cells - microbiology Fibronectin-binding protein Fibronectins - metabolism Gene expression Host-Pathogen Interactions Humans rac1 GTP-Binding Protein - metabolism Serotypes Streptococcus pyogenes Streptococcus pyogenes - genetics Streptococcus pyogenes - metabolism Streptococcus pyogenes - pathogenicity Tropism Virulence Factors - genetics Virulence Factors - metabolism
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