Neurologic manifestations of intravascular large B-cell lymphoma
Intravascular large B-cell lymphoma is a rare subtype of large B-cell lymphoma that affects various organs including the nervous system. The diagnosis is challenging and frequently made at autopsy. We report 5 cases with an array of neurologic manifestations. All patients were initially evaluated fo...
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Veröffentlicht in: | Neurology. Clinical practice 2016-02, Vol.6 (1), p.55-60 |
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creator | Tahsili-Fahadan, Pouya Rashidi, Armin Cimino, Patrick J Bucelli, Robert C Keyrouz, Salah G |
description | Intravascular large B-cell lymphoma is a rare subtype of large B-cell lymphoma that affects various organs including the nervous system. The diagnosis is challenging and frequently made at autopsy.
We report 5 cases with an array of neurologic manifestations. All patients were initially evaluated for alternative diagnoses. Three patients were diagnosed at autopsy, one with brain biopsy, and another with muscle biopsy. Muscle was involved in all 3 patients who had muscle tissue available for analysis.
Our observations suggest that random open muscle biopsy may present a high-yield, less invasive option for the diagnosis of this disorder. |
doi_str_mv | 10.1212/cpj.0000000000000185 |
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We report 5 cases with an array of neurologic manifestations. All patients were initially evaluated for alternative diagnoses. Three patients were diagnosed at autopsy, one with brain biopsy, and another with muscle biopsy. Muscle was involved in all 3 patients who had muscle tissue available for analysis.
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We report 5 cases with an array of neurologic manifestations. All patients were initially evaluated for alternative diagnoses. Three patients were diagnosed at autopsy, one with brain biopsy, and another with muscle biopsy. Muscle was involved in all 3 patients who had muscle tissue available for analysis.
Our observations suggest that random open muscle biopsy may present a high-yield, less invasive option for the diagnosis of this disorder.</description><subject>Review</subject><issn>2163-0402</issn><issn>2163-0933</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpdUNtKw0AQXUSxpfYPRPLoS-resmleRC1eKeqDPi-T3U2bkmTjblLo35vQC9WBYQbmzJkzB6FLgieEEnqj6tUEHweZRidoSIlgIU4YO933HNMBGnu_6kECE0aTczSgIiFTitkQ3b2b1tnCLnIVlFDlmfENNLmtfGCzIK8aB2vwqi3ABV0uTPAQKlMUQbEp66Ut4QKdZVB4M97VEfp-evyavYTzj-fX2f08VDzmTajAaJ1wTbHGEdFCZSwlLKJANQAkkY5jDSKJVSebJCzNOKRC0ISBiFINnI3Q7Za3btPSaGV6aYWsXV6C20gLufw7qfKlXNi15HHEpqwnuN4ROPvTdm_KMvf9K1AZ23rZGSJExCknHZRvocpZ753JDmcIlr3_cvb5Jv_7361dHUs8LO3dZr-k2II2</recordid><startdate>201602</startdate><enddate>201602</enddate><creator>Tahsili-Fahadan, Pouya</creator><creator>Rashidi, Armin</creator><creator>Cimino, Patrick J</creator><creator>Bucelli, Robert C</creator><creator>Keyrouz, Salah G</creator><general>Lippincott Williams & Wilkins</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201602</creationdate><title>Neurologic manifestations of intravascular large B-cell lymphoma</title><author>Tahsili-Fahadan, Pouya ; Rashidi, Armin ; Cimino, Patrick J ; Bucelli, Robert C ; Keyrouz, Salah G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-caedd94d20d051d6cf3b1352a2daaa95d77da697c216193bf4ab66293a65bda43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tahsili-Fahadan, Pouya</creatorcontrib><creatorcontrib>Rashidi, Armin</creatorcontrib><creatorcontrib>Cimino, Patrick J</creatorcontrib><creatorcontrib>Bucelli, Robert C</creatorcontrib><creatorcontrib>Keyrouz, Salah G</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Neurology. Clinical practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tahsili-Fahadan, Pouya</au><au>Rashidi, Armin</au><au>Cimino, Patrick J</au><au>Bucelli, Robert C</au><au>Keyrouz, Salah G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurologic manifestations of intravascular large B-cell lymphoma</atitle><jtitle>Neurology. Clinical practice</jtitle><addtitle>Neurol Clin Pract</addtitle><date>2016-02</date><risdate>2016</risdate><volume>6</volume><issue>1</issue><spage>55</spage><epage>60</epage><pages>55-60</pages><issn>2163-0402</issn><eissn>2163-0933</eissn><abstract>Intravascular large B-cell lymphoma is a rare subtype of large B-cell lymphoma that affects various organs including the nervous system. The diagnosis is challenging and frequently made at autopsy.
We report 5 cases with an array of neurologic manifestations. All patients were initially evaluated for alternative diagnoses. Three patients were diagnosed at autopsy, one with brain biopsy, and another with muscle biopsy. Muscle was involved in all 3 patients who had muscle tissue available for analysis.
Our observations suggest that random open muscle biopsy may present a high-yield, less invasive option for the diagnosis of this disorder.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>26918203</pmid><doi>10.1212/cpj.0000000000000185</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
subjects | Review |
title | Neurologic manifestations of intravascular large B-cell lymphoma |
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