Regulation of lipid synthesis by the RNA helicase Mov10 controls Wnt5a production

Expression of the Wnt ligand Wnt5a is frequently elevated in melanoma and is thought to be a critical regulator of cell movement during metastasis. However, the mechanisms regulating its expression are unknown. We find that the level of secreted Wnt5a varies by as much as 10-fold between cell lines...

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Veröffentlicht in:Oncogenesis (New York, NY) NY), 2015-06, Vol.4 (6), p.e154-e154
Hauptverfasser: Wang, W, Snyder, N, Worth, A J, Blair, I A, Witze, E S
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Sprache:eng
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