Tissue Metabonomic Phenotyping for Diagnosis and Prognosis of Human Colorectal Cancer

Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide and prognosis based on the conventional histological grading method for CRC remains poor. To better the situation, we analyzed the metabonomic signatures of 50 human CRC tissues and their adjacent non-involved tis...

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Veröffentlicht in:	Scientific reports 2016-02, Vol.6 (1), p.20790-20790, Article 20790
Hauptverfasser:	Tian, Yuan, Xu, Tangpeng, Huang, Jia, Zhang, Limin, Xu, Shan, Xiong, Bin, Wang, Yulan, Tang, Huiru
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1857 692/699/67/2327 Adult Aged Amino Acids - analysis Amino Acids - metabolism Biosynthesis Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Colorectal Neoplasms - surgery Energy metabolism Fatty Acids - analysis Fatty Acids - metabolism Female Gas Chromatography-Mass Spectrometry Humanities and Social Sciences Humans Magnetic Resonance Spectroscopy Male Metabolic Networks and Pathways Metabolism Metabolites Metabolome Metabolomics - instrumentation Metabolomics - methods Middle Aged multidisciplinary Neoplasm Grading Neoplasm Staging NMR Nuclear magnetic resonance Nucleotides Phenotyping Principal Component Analysis Prognosis ROC Curve Science Solid tumors Spectroscopy Tissues Tumor Microenvironment Tumors
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