Adiponectin downregulation is associated with volume overload-induced myocyte dysfunction in rats

Aim： Adiponectin has been reported to exert protective effects during pathological ventricular remodeling, but the role of adiponectin in volume overload-induced heart failure remains unclear. In this study we investigated the effect of adiponectin on cardiac myocyte contractile dysfunction followin...

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Veröffentlicht in:	Acta pharmacologica Sinica 2016-02, Vol.37 (2), p.187-195
Hauptverfasser:	Wang, Li-li, Miller, Dori, Wanders, Desiree, Nanayakkara, Gayani, Amin, Rajesh, Judd, Robert, Morrison, Edward E, Zhong, Ju-ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - blood Adiponectin - metabolism AMP-Activated Protein Kinases - metabolism Animals Biomedical and Life Sciences Biomedicine Calcium - metabolism Cells, Cultured Down-Regulation Heart Failure - blood Heart Failure - etiology Heart Failure - metabolism Heart Failure - pathology Immunology Internal Medicine Male Medical Microbiology Myocytes, Cardiac - metabolism Myocytes, Cardiac - pathology Original original-article Pharmacology/Toxicology Rats Rats, Sprague-Dawley Vaccine 制剂处方药学药理
Online-Zugang:	Volltext
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