Lysine acetyltransfer supports platelet function

Summary Background and Objectives The reversible acetylation of protein lysine ε‐amino groups, catalyzed by lysine acetyltransferases and deacetylases, serves as a molecular switch in the orchestration of diverse cellular activities. Here, we aimed to investigate the role of lysine acetyltransfer in...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2015-10, Vol.13 (10), p.1908-1917
Hauptverfasser:	Aslan, J. E., Rigg, R. A., Nowak, M. S., Loren, C. P., Baker‐Groberg, S. M., Pang, J., David, L. L., McCarty, O. J. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation acetyltransferases actin Actin Cytoskeleton - enzymology Actins - metabolism Blood Platelets - drug effects Blood Platelets - enzymology Blood Proteins - metabolism Carrier Proteins - pharmacology Cell Shape Computational Biology Enzyme Activation Humans Lysine metabolism p300 acetyltransferase p300-CBP Transcription Factors - blood Peptides - pharmacology Platelet Activation - drug effects Platelet Aggregation platelets Protein Processing, Post-Translational Proteomics - methods src-Family Kinases - metabolism
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