Gene expression identifies heterogeneity of metastatic behavior among gastrointestinal stromal tumors

Adjuvant imatinib is useful in patients with gastrointestinal stromal tumors (GIST) at high risk of recurrence. At present, the risk of recurrence is determined based on tumor size, mitotic rate, tumor site, and tumor rupture. Previous studies using various biochemical pathways identified gene expre...

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Veröffentlicht in:	Journal of translational medicine 2016-02, Vol.14 (51), p.51-51, Article 51
Hauptverfasser:	Skubitz, Keith M, Geschwind, Kate, Xu, Wayne W, Koopmeiners, Joseph S, Skubitz, Amy P N
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Care and treatment Cell Line, Tumor Cluster Analysis Clustering Complications and side effects Confidence Intervals Data analysis Databases, Genetic Diagnosis Gastrointestinal Stromal Tumors - genetics Gastrointestinal Stromal Tumors - pathology Gene expression Gene Expression Regulation, Neoplastic Genetic Heterogeneity Humans Kaplan-Meier Estimate Kinases Medical prognosis Metastasis Mutation Neoplasm Metastasis Neoplasm Recurrence, Local - pathology Ovarian cancer Probability Risk Factors Sarcoma Software Studies Tumors
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