Roles of Caveolin-1 in Angiotensin II–Induced Hypertrophy and Inward Remodeling of Cerebral Pial Arterioles

Angiotensin II (Ang II) is a major determinant of inward remodeling and hypertrophy in pial arterioles that may have an important role in stroke during chronic hypertension. Previously, we found that epidermal growth factor receptor is critical in Ang II–mediated hypertrophy that may involve caveoli...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2016-03, Vol.67 (3), p.623-629
Hauptverfasser:	Umesalma, Shaikamjad, Houwen, Frederick Keith, Baumbach, Gary L, Chan, Siu-Lung
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - toxicity Animals Arterioles - metabolism Arterioles - pathology Caveolin 1 - biosynthesis Caveolin 1 - genetics Disease Models, Animal Gene Expression Regulation Hypertension - chemically induced Hypertension - genetics Hypertension - metabolism Hypertrophy - chemically induced Hypertrophy - genetics Hypertrophy - pathology Mice Mice, Inbred C57BL RNA - genetics Vascular Remodeling - genetics
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