Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer

There is strong epidemiologic evidence linking chronic exposure to inorganic arsenic (iAs) to myriad adverse health effects, including cancer of the bladder. We set out to identify DNA methylation patterns associated with arsenic and its metabolites in exfoliated urothelial cells (EUCs) that origina...

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Veröffentlicht in:Chemical research in toxicology 2015-06, Vol.28 (6), p.1144-1155
Hauptverfasser: Rager, Julia E, Tilley, Sloane K, Tulenko, Samantha E, Smeester, Lisa, Ray, Paul D, Yosim, Andrew, Currier, Jenna M, Ishida, María C, González-Horta, Maria del Carmen, Sánchez-Ramírez, Blanca, Ballinas-Casarrubias, Lourdes, Gutiérrez-Torres, Daniela S, Drobná, Zuzana, Del Razo, Luz M, García-Vargas, Gonzalo G, Kim, William Y, Zhou, Yi-Hui, Wright, Fred A, Stýblo, Miroslav, Fry, Rebecca C
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Sprache:eng
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