Evaluation of an epithelial plasticity biomarker panel in men with localized prostate cancer

Background: Given the potential importance of epithelial plasticity (EP) to cancer metastasis, we sought to investigate biomarkers related to EP in men with localized prostate cancer (PC) for the association with time to PSA recurrence and other clinical outcomes after surgery. Methods: Men with loc...

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Veröffentlicht in:	Prostate cancer and prostatic diseases 2016-03, Vol.19 (1), p.40-45
Hauptverfasser:	Armstrong, A J, Healy, P, Halabi, S, Vollmer, R, Lark, A, Kemeny, G, Ware, K, Freedland, S J
Format:	Artikel
Sprache:	eng
Schlagworte:	13/105 692/53/2422 82 82/1 82/51 Aged Analysis Antibodies Biomarkers Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Biomedical and Life Sciences Biomedicine Cadherins - biosynthesis Cadherins - genetics Cancer Research Cancer surgery Care and treatment Cell Plasticity - genetics Diagnosis Disease-Free Survival E-cadherin Epithelial Cells - metabolism Epithelial Cells - pathology Health care facilities Health risks Homeodomain Proteins - biosynthesis Homeodomain Proteins - genetics Humans Intermediate filament proteins Ki-67 Antigen - biosynthesis Ki-67 Antigen - genetics Male Mesenchyme Metastases Middle Aged N-Cadherin Neoplasm Recurrence, Local - blood Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - surgery Nuclear Proteins - biosynthesis Nuclear Proteins - genetics original-article Plastic properties Plasticity Prostate cancer Prostate-Specific Antigen - blood Prostatectomy Prostatic Neoplasms - blood Prostatic Neoplasms - genetics Prostatic Neoplasms - mortality Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Risk Snail Family Transcription Factors Surgery Tissue Array Analysis Tissues Transcription Factors - biosynthesis Transcription Factors - genetics Twist-Related Protein 1 - biosynthesis Twist-Related Protein 1 - genetics Urological surgery Vimentin Vimentin - biosynthesis Vimentin - genetics Zinc Finger E-box-Binding Homeobox 1
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