Fox-Fordyce Disease

Physical examination showed skin coloured papules and alopecia [Figure 1A], which showed no fluorescence under a Wood’s lamp. The histology of the skin biopsy indicated an inflammatory infiltrate of lymphocytes affecting the follicle [Figure 1C] and the obstruction of the eccrine and apocrine sweat glands [Figure 1D]. The underlying aetiology of FF remains unclear, although a history of trauma caused by laser hair removal or hormonal factors may be triggers.1–4 The pathophysiology consists of the obstruction of the apocrine gland duct due to the insertion of a keratin plug in the hair follicle wall.