Effect of miR-146a/bFGF/PEG-PEI Nanoparticles on Inflammation Response and Tissue Regeneration of Human Dental Pulp Cells

Introduction. Inflammation in dental pulp cells (DPCs) initiated by Lipopolysaccharide (LPS) results in dental pulp necrosis. So far, whether there is a common system regulating inflammation response and tissue regeneration remains unknown. miR-146a is closely related to inflammation. Basic fibrobla...

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Veröffentlicht in:	BioMed research international 2016-01, Vol.2016 (2016), p.1-12
Hauptverfasser:	Wei, Xi, Cheung, Gary Shunpan, Shu, Shan, Liu, Lu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Analysis Biocompatibility Cell growth Cell Proliferation - drug effects Cytokines Cytotoxicity Dental Pulp - cytology Dentistry Drug Carriers - chemistry Efficiency Fibroblast Growth Factor 2 - chemistry Fibroblast Growth Factor 2 - pharmacokinetics Fibroblast Growth Factor 2 - pharmacology Fibroblast growth factors Fourier transforms Gene therapy Genetic vectors Humans Hydrogels Infection Inflammation Lipopolysaccharides - adverse effects MicroRNAs - chemistry MicroRNAs - pharmacokinetics MicroRNAs - pharmacology Mitogens Nanoparticles Nanoparticles - chemistry Polyethylene glycol Polyethylene Glycols - chemistry Polyethyleneimine - chemistry Polymer solubility Polyols Proteins Pulpitis - chemically induced Pulpitis - metabolism Regeneration - drug effects Tissue engineering Vectors (Biology) Wound healing Young Adult
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