Proteomic Mapping of the Human Mitochondrial Intermembrane Space in Live Cells via Ratiometric APEX Tagging

Obtaining complete protein inventories for subcellular regions is a challenge that often limits our understanding of cellular function, especially for regions that are impossible to purify and are therefore inaccessible to traditional proteomic analysis. We recently developed a method to map proteom...

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Veröffentlicht in:Molecular cell 2014-07, Vol.55 (2), p.332-341
Hauptverfasser: Hung, Victoria, Zou, Peng, Rhee, Hyun-Woo, Udeshi, Namrata D., Cracan, Valentin, Svinkina, Tanya, Carr, Steven A., Mootha, Vamsi K., Ting, Alice Y.
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