Identification of drugs as single agents or in combination to prevent carcinoma dissemination in a microfluidic 3D environment

Experiments were performed in a modified microfluidic platform recapitulating part of the in vivo tumor microenvironment by co-culturing carcinoma cell aggregates embedded in a three-dimensional (3D) collagen scaffold with human umbilical vein endothelial cells (HUVECs). HUVECs were seeded in one ch...

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Veröffentlicht in:Oncotarget 2015-11, Vol.6 (34), p.36603-36614
Hauptverfasser: Bai, Jing, Tu, Ting-Yuan, Kim, Choong, Thiery, Jean Paul, Kamm, Roger D
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Sprache:eng
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