Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population

More than 30 independent single-nucleotide polymorphisms (SNPs) have been associated with Alzheimer's disease (AD) risk by genome-wide association studies (GWAS) in European. We aimed to confirm these SNPs in Chinese Han and investigate the utility of these genetic markers. We randomly divided...

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Veröffentlicht in:	Oncotarget 2015-11, Vol.6 (35), p.36955-36964
Hauptverfasser:	Xiao, Qianyi, Liu, Zhi-Jun, Tao, Sha, Sun, Yi-Min, Jiang, Deke, Li, Hong-Lei, Chen, Haitao, Liu, Xu, Lapin, Brittany, Wang, Chi-Hsiung, Zheng, S Lilly, Xu, Jianfeng, Wu, Zhi-Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - epidemiology Alzheimer Disease - genetics Analysis of Variance Asian Continental Ancestry Group - genetics Biomarkers - metabolism Case-Control Studies China - epidemiology Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Male Middle Aged Polymorphism, Single Nucleotide - genetics Predictive Value of Tests Research Paper: Gerotarget (Focus on Aging) Risk Assessment Risk Factors
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