Lysine-specific demethylase 1 promotes tumorigenesis and predicts prognosis in gallbladder cancer

Gallbladder Cancer (GBC), characterized by invasive growth and infiltrative dissemination, is difficult to diagnose and has poor prognosis. Emerging evidence demonstrates that Lysine-Specific Demethylase 1 (LSD1) has important roles in carcinogenesis, proliferation and metastasis. We studied the rol...

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Veröffentlicht in:	Oncotarget 2015-10, Vol.6 (32), p.33065-33076
Hauptverfasser:	Lian, Shi Xian, Shao, Ye Bo, Liu, Hou Bao, He, Jun Yi, Lu, Wei Qi, Zhang, Yong, Jiang, Ying, Zhu, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinogenesis - genetics Carcinogenesis - metabolism Cell Line, Tumor Cell Proliferation - physiology Down-Regulation Epithelial-Mesenchymal Transition Gallbladder Neoplasms - enzymology Gallbladder Neoplasms - genetics Gallbladder Neoplasms - pathology Gene Knockdown Techniques Heterografts Histone Demethylases - genetics Histone Demethylases - metabolism Humans Male Mice Mice, Nude Predictive Value of Tests Prognosis Research Paper Up-Regulation
Online-Zugang:	Volltext
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