Urinary beta-aminoisobutyric acid excretion in thalassaemia

Urinary beta-aminoisobutyric acid excretion in thalassaemia

The quantity of beta-aminoisobutyric acid (BAIB) excreted in the urine of patients with an intact spleen suffering from thalassaemia major appears to be proportional to the number of the circulating normoblasts and inversely proportional to the haemoglobin level. After splenectomy only minute amount...

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Veröffentlicht in:Journal of clinical pathology 1969-03, Vol.22 (2), p.154-157
Hauptverfasser: Fessas, Ph, Koniavitis, A., Zeis, P. M.
Format: Artikel
Sprache:eng
Schlagworte:
Aminoisobutyric Acids - urine
Anemia, Hypochromic - urine
Anemia, Sickle Cell - urine
Hemoglobinometry
Humans
Splenectomy
Thalassemia - urine
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container_title Journal of clinical pathology
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creator Fessas, Ph
Koniavitis, A.
Zeis, P. M.
description The quantity of beta-aminoisobutyric acid (BAIB) excreted in the urine of patients with an intact spleen suffering from thalassaemia major appears to be proportional to the number of the circulating normoblasts and inversely proportional to the haemoglobin level. After splenectomy only minute amounts of BAIB are excreted. Transfusion constantly, but temporarily, reduces urinary excretion of beta-aminoisobutyric acid. Other anaemic but non-thalassaemic patients may excrete low levels.
doi_str_mv 10.1136/jcp.22.2.154
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subjects Aminoisobutyric Acids - urine
Anemia, Hypochromic - urine
Anemia, Sickle Cell - urine
Hemoglobinometry
Humans
Splenectomy
Thalassemia - urine
title Urinary beta-aminoisobutyric acid excretion in thalassaemia
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