Bioengineering Human Myocardium on Native Extracellular Matrix

RATIONALE:More than 25 million individuals have heart failure worldwide, with ≈4000 patients currently awaiting heart transplantation in the United States. Donor organ shortage and allograft rejection remain major limitations with only ≈2500 hearts transplanted each year. As a theoretical alternativ...

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Veröffentlicht in:	Circulation research 2016-01, Vol.118 (1), p.56-72
Hauptverfasser:	Guyette, Jacques P, Charest, Jonathan M, Mills, Robert W, Jank, Bernhard J, Moser, Philipp T, Gilpin, Sarah E, Gershlak, Joshua R, Okamoto, Tatsuya, Gonzalez, Gabriel, Milan, David J, Gaudette, Glenn R, Ott, Harald C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bioengineering - methods Cell Differentiation - physiology Extracellular Matrix - physiology Female Humans Male Middle Aged Myocardium - cytology Pluripotent Stem Cells - physiology
Online-Zugang:	Volltext
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