Measure transcript integrity using RNA-seq data

Stored biological samples with pathology information and medical records are invaluable resources for translational medical research. However, RNAs extracted from the archived clinical tissues are often substantially degraded. RNA degradation distorts the RNA-seq read coverage in a gene-specific man...

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Veröffentlicht in:	BMC bioinformatics 2016-02, Vol.17 (1), p.58-58, Article 58
Hauptverfasser:	Wang, Liguo, Nie, Jinfu, Sicotte, Hugues, Li, Ying, Eckel-Passow, Jeanette E, Dasari, Surendra, Vedell, Peter T, Barman, Poulami, Wang, Liewei, Weinshiboum, Richard, Jen, Jin, Huang, Haojie, Kohli, Manish, Kocher, Jean-Pierre A
Format:	Artikel
Sprache:	eng
Schlagworte:	Genome, Human High-Throughput Nucleotide Sequencing - standards Humans Male Methodology Prostatic Neoplasms - genetics Quality Control RNA Stability - genetics RNA, Messenger - chemistry RNA, Messenger - genetics RNA, Neoplasm - chemistry RNA, Neoplasm - genetics Sequence Analysis, RNA - standards
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