Rapid model exploration for complex hierarchical data: application to pharmacokinetics of insulin aspart

We consider situations, which are common in medical statistics, where we have a number of sets of response data, from different individuals, say, potentially under different conditions. A parametric model is defined for each set of data, giving rise to a set of random effects. Our goal here is to ef...

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Veröffentlicht in:Statistics in medicine 2015-10, Vol.34 (23), p.3144-3158
Hauptverfasser: Goudie, Robert J. B., Hovorka, Roman, Murphy, Helen R., Lunn, David
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Sprache:eng
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