Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat

Cadmium (Cd) is a nephrotoxic environmental pollutant that causes insidious injury to the proximal tubule that results in severe polyuria and proteinuria. Cystatin C is a low molecular weight protein that is being evaluated as a serum and urinary biomarker for various types of ischemic and nephrotox...

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Veröffentlicht in:	Biometals 2016-02, Vol.29 (1), p.131-146
Hauptverfasser:	Prozialeck, Walter C., VanDreel, Aaron, Ackerman, Christopher D., Stock, Ian, Papaeliou, Alexander, Yasmine, Christian, Wilson, Kristen, Lamar, Peter C., Sears, Victoria L., Gasiorowski, Joshua Z., DiNovo, Karyn M., Vaidya, Vishal S., Edwards, Joshua R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioaccumulation Biochemistry Biomarkers Biomarkers - blood Biomarkers - urine Biomedical and Life Sciences Cadmium Cadmium - administration & dosage Cadmium - toxicity Cell Adhesion Molecules - blood Cell Biology Creatinine - blood Cystatin C - blood Cystatin C - urine Cytoplasm Environmental Pollutants Excretion Humans Injuries Kidney Tubules, Proximal - injuries Kidney Tubules, Proximal - metabolism Kidney Tubules, Proximal - pathology Kidneys Life Sciences Male Medicine/Public Health Microbiology Pharmacology/Toxicology Plant Physiology Proteins Proteinuria Rats Serums Toxicity Uptakes
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