Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Compensates for Interleukin-6 in Initial B Cell Activation

Interleukin 6 (IL-6) is considered a proliferation and survival factor for B cells. To assess the role of IL-6 in Kaposi sarcoma-associated herpesvirus (KSHV) latency, KSHV latency locus-transgenic mice (referred to as latency mice) lacking IL-6 were evaluated. IL-6(-/-) latency mice had the same ph...

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Veröffentlicht in:	Journal of virology 2016-02, Vol.90 (4), p.2150-2154
Hauptverfasser:	Sin, Sang-Hoon, Kang, Sun Ah, Kim, Yongbaek, Eason, Anthony, Tan, Kelly, An, Hyowon, Dittmer, Dirk P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocytes - virology Herpesvirus 8, Human - physiology Human herpesvirus 8 Interleukin-6 - deficiency Interleukin-6 - metabolism Kaposi's sarcoma-associated herpesvirus Lymphocyte Activation Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Pathogenesis and Immunity Virus Latency
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