Relationship between regulatory T cells subsets and lipid profile in dyslipidemic patients: a longitudinal study during atorvastatin treatment

The CD4+ T-lymphocytes and their subtype CD4 + CD25(high)FoxP3+ regulatory T cells are receiving growing interest as major regulators of atherogenesis. We sought to investigate 1) whether the CD4 + cell subsets were expressed differently in dyslipidemic patients (Pts) and healthy subjects (HS) and 2...

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Veröffentlicht in:	BMC cardiovascular disorders 2016-01, Vol.16 (26), p.26-26, Article 26
Hauptverfasser:	Guasti, Luigina, Maresca, Andrea Maria, Schembri, Laura, Rasini, Emanuela, Dentali, Francesco, Squizzato, Alessandro, Klersy, Catherine, Robustelli Test, Laura, Mongiardi, Christian, Campiotti, Leonardo, Ageno, Walter, Grandi, Anna Maria, Cosentino, Marco, Marino, Franca
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apolipoproteins A - metabolism Apolipoproteins B - metabolism Atorvastatin Calcium - therapeutic use C-Reactive Protein - immunology Case-Control Studies CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Cell Proliferation Cell Survival - immunology Cholesterol, HDL - metabolism Cholesterol, LDL - metabolism Complications and side effects Drug therapy Dyslipidemias Dyslipidemias - drug therapy Dyslipidemias - immunology Dyslipidemias - metabolism Enzyme-Linked Immunosorbent Assay Female Forkhead Transcription Factors - genetics Forkhead Transcription Factors - immunology Genetic aspects Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use In Vitro Techniques Interleukin-10 - genetics Interleukin-10 - immunology Longitudinal Studies Male Middle Aged Physiological aspects Real-Time Polymerase Chain Reaction RNA, Messenger - metabolism T cells T-Lymphocyte Subsets - immunology T-Lymphocytes, Regulatory - immunology Transforming Growth Factor beta - genetics Transforming Growth Factor beta - immunology Triglycerides - metabolism
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