Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer

The effects of treatments to programmed death ligand-1 (PD-L1) expression is unknown. The aim of this study was to investigate the impact of neoadjuvant chemotherapy (NACT) on PD-L1 expression in non-small cell lung cancer (NSCLC) patients. PD-L1 expression was detected by immunohistochemistry (IHC)...

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Veröffentlicht in:	Scientific reports 2016-01, Vol.6 (1), p.20090-20090, Article 20090
Hauptverfasser:	Sheng, Jin, Fang, Wenfeng, Yu, Juan, Chen, Nan, Zhan, Jianhua, Ma, Yuxiang, Yang, Yunpeng, Huang, Yan, Zhao, Hongyun, Zhang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1612/1350 692/4028/67/1612/1350 Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Apoptosis B7-H1 Antigen - genetics B7-H1 Antigen - metabolism Biomarkers, Tumor Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Chemotherapy Female Gene Expression Regulation Humanities and Social Sciences Humans Immunohistochemistry Kaplan-Meier Estimate Ligands Lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - metabolism Lung Neoplasms - mortality Lung Neoplasms - pathology Male Middle Aged multidisciplinary Mutation Neoplasm Staging Non-small cell lung carcinoma PD-L1 protein Prognosis Science Treatment Outcome Tumor cells Tumors
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