High Throughput Label Free Measurement of Cancer Cell Adhesion Kinetics Under Hemodynamic Flow

The kinetics of receptor-mediated cell adhesion to extracellular matrix and adherent cell monolayers plays a key role in many physiological and pathological processes including cancer metastasis. Within this process the presence of fluidic shear forces is a key regulator of binding equilibrium and k...

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Veröffentlicht in:	Scientific reports 2016-01, Vol.6 (1), p.19854-19854, Article 19854
Hauptverfasser:	Spencer, Adrianne, Baker, Aaron B.
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/106 13/62 49 631/154/1435 692/4028/67 9/10 9/30 Adhesion Blood Flow Velocity Cancer Cell Adhesion Cell adhesion & migration Cell Line, Tumor Drug screening Extracellular matrix Extracellular Matrix - metabolism Extracellular Matrix - pathology Humanities and Social Sciences Humans Kinetics Mechanical stimuli Metastases Metastasis multidisciplinary Neoplasm Metastasis Neoplasms - metabolism Neoplasms - pathology Platelets Science Shear Strength Shear stress
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