A Gene Expression Signature Associated with Overall Survival in Patients with Hepatocellular Carcinoma Suggests a New Treatment Strategy

Despite improvements in the management of liver cancer, the survival rate for patients with hepatocellular carcinoma (HCC) remains dismal. The survival benefit of systemic chemotherapy for the treatment of liver cancer is only marginal. Although the reasons for treatment failure are multifactorial,...

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Veröffentlicht in:	Molecular pharmacology 2016-02, Vol.89 (2), p.263-272
Hauptverfasser:	Gillet, Jean-Pierre, Andersen, Jesper B., Madigan, James P., Varma, Sudhir, Bagni, Rachel K., Powell, Katie, Burgan, William E., Wu, Chung-Pu, Calcagno, Anna Maria, Ambudkar, Suresh V., Thorgeirsson, Snorri S., Gottesman, Michael M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - mortality Cell Line, Tumor Cohort Studies Gene Expression Regulation, Neoplastic Humans Liver Neoplasms - drug therapy Liver Neoplasms - genetics Liver Neoplasms - mortality Survival Rate - trends Treatment Outcome
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