Identification of miR-15b as a transformation-related factor in mantle cell lymphoma

Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma with a poor prognosis. It is characterized by the t(11;14)(q13;q32) translocation, resulting in overexpression of CCND1. Morphologically, MCL is categorised into two types: classical MCL (cMCL) and aggressive MCL (aMCL), with a proportion o...

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Veröffentlicht in:	International journal of oncology 2016-02, Vol.48 (2), p.485-492
Hauptverfasser:	ARAKAWA, FUMIKO, KIMURA, YOSHIZO, YOSHIDA, NORIAKI, MIYOSHI, HIROAKI, DOI, ATUSHI, YASUDA, KAORI, NAKAJIMA, KAZUTAKA, KIYASU, JUNICHI, NIINO, DAISUKE, SUGITA, YASUO, TASHIRO, KOSUKE, KUHARA, SATORU, SETO, MASAO, OHSHIMA, KOICHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Apoptosis - genetics Biomarkers, Tumor - genetics Cell cycle Cell Cycle - genetics Classification Cyclin D1 - genetics Development and progression Female Gene expression Gene Expression Profiling - methods Gene Expression Regulation, Neoplastic - genetics Genetic aspects Health aspects Humans Identification and classification in situ hybridization laser microdissection Lasers Lymphoma Lymphoma, B-Cell - genetics Lymphoma, Mantle-Cell - genetics Male Mantle cell lymphoma Microarray Analysis - methods MicroRNA MicroRNAs MicroRNAs - genetics Middle Aged miR-15b miRNA microarray Morphology Prognosis Transformation, Genetic - genetics Up-Regulation - genetics
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