Multidrug-Resistant Tuberculosis Treatment Outcomes in Relation to Treatment and Initial Versus Acquired Second-Line Drug Resistance

Background. Resistance to second-line drugs develops during treatment of multidrug-resistant (MDR) tuberculosis, but the impact on treatment outcome has not been determined. Methods. Patients with MDR tuberculosis starting second-line drug treatment were enrolled in a prospective cohort study. Sputu...

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Veröffentlicht in:	Clinical infectious diseases 2016-02, Vol.62 (4), p.418-430
Hauptverfasser:	Cegielski, J. Peter, Kurbatova, Ekaterina, van der Walt, Martie, Brand, Jeannette, Ershova, Julia, Tupasi, Thelma, Caoili, Janice Campos, Dalton, Tracy, Contreras, Carmen, Yagui, Martin, Bayona, Jaime, Kvasnovsky, Charlotte, Leimane, Vaira, Kuksa, Liga, Chen, Michael P., Via, Laura E., Hwang, Soo Hee, Wolfgang, Melanie, Volchenkov, Grigory V., Somova, Tatiana, Smith, Sarah E., Akksilp, Somsak, Wattanaamornkiet, Wanpen, Kim, Hee Jin, Kim, Chang-ki, Kazennyy, Boris Y., Khorosheva, Tatiana, Kliiman, Kai, Viiklepp, Piret, Jou, Ruwen, Huang, Angela Song-En, Vasilyeva, Irina A., Demikhova, Olga V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged and Commentaries Antitubercular Agents - therapeutic use ARTICLES AND COMMENTARIES Clinical outcomes Drug resistance Drug Resistance, Multiple, Bacterial Female Humans Male Medical treatment Middle Aged Multidrug resistant organisms Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - isolation & purification Prospective Studies Sputum - microbiology Treatment Outcome Tuberculosis Tuberculosis, Multidrug-Resistant - drug therapy Young Adult
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