Internalization and Axonal Transport of the HIV Glycoprotein gp120

The HIV glycoprotein gp120, a neurotoxic HIV glycoprotein that is overproduced and shed by HIV-infected macrophages, is associated with neurological complications of HIV such as distal sensory polyneuropathy, but interactions of gp120 in the peripheral nervous system remain to be characterized. Here...

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Veröffentlicht in:	ASN neuro 2015-01, Vol.7 (1)
Hauptverfasser:	Berth, Sarah, Caicedo, Hector Hugo, Sarma, Tulika, Morfini, Gerardo, Brady, Scott T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-HIV Agents - pharmacology Axonal Transport - drug effects Axonal Transport - physiology Benzylamines Cell Differentiation - physiology Cells, Cultured Cyclams Cyclic AMP - pharmacology Embryo, Mammalian Ganglia, Spinal - cytology Heterocyclic Compounds - pharmacology HIV Envelope Protein gp120 - metabolism HIV Envelope Protein gp120 - pharmacology Neuroblastoma - pathology Neurons - pathology Original Protein Binding Protein Transport - drug effects Protein Transport - physiology Rats Receptors, CXCR4 - metabolism Signal Transduction Time Factors
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