The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development

RNA-binding proteins participate in a complex array of posttranscriptional controls essential to cell type specification and somatic development. Despite their detailed biochemical characterizations, the degree to which each RNA-binding protein impacts mammalian embryonic development remains incompl...

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Veröffentlicht in:	Molecular and cellular biology 2016-01, Vol.36 (2), p.304-319
Hauptverfasser:	Ghanem, Louis R., Kromer, Andrew, Silverman, Ian M., Chatterji, Priya, Traxler, Elizabeth, Penzo-Mendez, Alfredo, Weiss, Mitchell J., Stanger, Ben Z., Liebhaber, Stephen A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Carrier Proteins - genetics Carrier Proteins - metabolism Embryo, Mammalian - metabolism Gene Deletion Gene Expression Regulation Genetic Loci Hematopoiesis Mice - embryology Mice - genetics Molecular Sequence Data RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Transcriptome
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