Mycobacterium tuberculosis copper-regulated protein SocB is an intrinsically disordered protein that folds upon interaction with a synthetic phospholipid bilayer

ABSTRACT Multiple genes in Mycobacterium tuberculosis (Mtb) are regulated by copper including socAB (small orf induced by copper A and B), which is induced by copper and repressed by RicR (regulated in copper repressor). socA and socB encode hypothetical proteins of 61 and 54 amino acids, respective...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2016-02, Vol.84 (2), p.193-200
Hauptverfasser:	Nowicka, Urszula, Hoffman, Morgan, Randles, Leah, Shi, Xiaoshan, Khavrutskii, Lyuba, Stefanisko, Karen, Tarasova, Nadya I., Darwin, K. Heran, Walters, Kylie J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - chemistry Bacterial Proteins - metabolism Copper - chemistry Copper - metabolism intrinsically disordered proteins Intrinsically Disordered Proteins - chemistry Intrinsically Disordered Proteins - metabolism Lipid Bilayers - chemistry Lipid Bilayers - metabolism membrane protein Membrane Proteins - chemistry Membrane Proteins - metabolism Molecular Sequence Data Mycobacterium tuberculosis Mycobacterium tuberculosis (Mtb) Mycobacterium tuberculosis - enzymology SocB synthetic phospholipid bilayer
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