Serotonin 1A and Serotonin 4 Receptors: Essential Mediators of the Neurogenic and Behavioral Actions of Antidepressants

Selective serotonin reuptake inhibitors are the mostly widely used treatment for major depressive disorders and also are prescribed for several anxiety disorders. However, similar to most antidepressants, selective serotonin reuptake inhibitors suffer from two major problems: They only show benefici...

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Veröffentlicht in:	The Neuroscientist 2016-02, Vol.22 (1), p.26-45
Hauptverfasser:	Samuels, Benjamin Adam, Mendez-David, Indira, Faye, Charlène, David, Sylvain André, Pierz, Kerri A., Gardier, Alain M., Hen, René, David, Denis J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents - pharmacology Antidepressive Agents - therapeutic use Hippocampus - drug effects Hippocampus - metabolism Humans Mood Disorders - drug therapy Mood Disorders - metabolism Neurogenesis - drug effects Neurogenesis - physiology Receptor, Serotonin, 5-HT1A - metabolism Receptors, Serotonin, 5-HT4 - metabolism
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