PIK3CA polymorphisms associated with susceptibility to hepatocellular carcinoma

Our study was carried out to explore the relationship of PIK3CA rs17849071 and rs17849079 polymorphisms with the susceptibility to hepatocellular carcinoma (HCC) in Chinese Han population. 150 HCC patients and 152 healthy individuals were recruited in the case and control groups respectively. The ge...

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Veröffentlicht in:	International journal of clinical and experimental pathology 2015-01, Vol.8 (11), p.15255-15259
Hauptverfasser:	Li, Hong-Guang, Liu, Fang-Feng, Zhu, Hua-Qiang, Zhou, Xu, Lu, Jun, Chang, Hong, Hu, Jin-Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Asian Continental Ancestry Group - genetics Biomarkers, Tumor - genetics Carcinoma, Hepatocellular - enzymology Carcinoma, Hepatocellular - ethnology Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology Case-Control Studies Chi-Square Distribution China - epidemiology Class I Phosphatidylinositol 3-Kinases Female Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Haplotypes Heterozygote Homozygote Humans Linkage Disequilibrium Liver Neoplasms - enzymology Liver Neoplasms - ethnology Liver Neoplasms - genetics Liver Neoplasms - pathology Male Middle Aged Odds Ratio Original Phenotype Phosphatidylinositol 3-Kinases - genetics Polymorphism, Genetic Risk Assessment Risk Factors
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