Lung mechanics in subjects showing increased residual volume without bronchial obstruction
Fourteen subjects showing an increase of residual volume (RV) without any clinical or functional signs of bronchial obstruction were studied. Maximum expiratory flow volume (MEFV) curves were obtained with a pressure-corrected volume plethysmograph. Static pressure-volume curves were obtained by ste...
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| Veröffentlicht in: | Thorax 1980-06, Vol.35 (6), p.461-466 |
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| creator | Vulterini, S Bianco, M R Pellicciotti, L Sidoti, A M |
| description | Fourteen subjects showing an increase of residual volume (RV) without any clinical or functional signs of bronchial obstruction were studied. Maximum expiratory flow volume (MEFV) curves were obtained with a pressure-corrected volume plethysmograph. Static pressure-volume curves were obtained by stepwise interruption of a slow expiration from total lung capacity (TLC) to RV. Static compliance was measured by the slope of pressure-volume curve between functional residual capacity (FRC) and FRC+20% of TLC. Maximum flow static recoil (MFSR) curves were constructed by plotting MEF obtained from MEFV curves against elastic pressure (Pst) obtained from pressure-volume curves at the same lung volumes. Most patients demonstrated a decrease of MEF 50% and 25% of VC. From the MFSR curves it was clear that this reduction was not the result of increased airways resistance, but rather of loss of elastic recoil. Most patients showed a significant decrease of Pst at different volumes and changes seem likely to be evidence of emphysema. |
| doi_str_mv | 10.1136/thx.35.6.461 |
| format | Article |
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Maximum expiratory flow volume (MEFV) curves were obtained with a pressure-corrected volume plethysmograph. Static pressure-volume curves were obtained by stepwise interruption of a slow expiration from total lung capacity (TLC) to RV. Static compliance was measured by the slope of pressure-volume curve between functional residual capacity (FRC) and FRC+20% of TLC. Maximum flow static recoil (MFSR) curves were constructed by plotting MEF obtained from MEFV curves against elastic pressure (Pst) obtained from pressure-volume curves at the same lung volumes. Most patients demonstrated a decrease of MEF 50% and 25% of VC. From the MFSR curves it was clear that this reduction was not the result of increased airways resistance, but rather of loss of elastic recoil. Most patients showed a significant decrease of Pst at different volumes and changes seem likely to be evidence of emphysema.</description><identifier>ISSN: 0040-6376</identifier><identifier>EISSN: 1468-3296</identifier><identifier>DOI: 10.1136/thx.35.6.461</identifier><identifier>PMID: 7434303</identifier><identifier>CODEN: THORA7</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Thoracic Society</publisher><subject>Adult ; Airway Resistance ; Female ; Forced Expiratory Volume ; Humans ; Lung - physiopathology ; Lung Compliance ; Lung Diseases - physiopathology ; Lung Volume Measurements ; Male ; Middle Aged ; Residual Volume</subject><ispartof>Thorax, 1980-06, Vol.35 (6), p.461-466</ispartof><rights>Copyright BMJ Publishing Group LTD Jun 1980</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b476t-df62ce50faa07b6dfba3f129ee4693646c731d7b17d8f7aa3421c86c9a865b9f3</citedby><cites>FETCH-LOGICAL-b476t-df62ce50faa07b6dfba3f129ee4693646c731d7b17d8f7aa3421c86c9a865b9f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC471311/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC471311/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7434303$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vulterini, S</creatorcontrib><creatorcontrib>Bianco, M R</creatorcontrib><creatorcontrib>Pellicciotti, L</creatorcontrib><creatorcontrib>Sidoti, A M</creatorcontrib><title>Lung mechanics in subjects showing increased residual volume without bronchial obstruction</title><title>Thorax</title><addtitle>Thorax</addtitle><description>Fourteen subjects showing an increase of residual volume (RV) without any clinical or functional signs of bronchial obstruction were studied. Maximum expiratory flow volume (MEFV) curves were obtained with a pressure-corrected volume plethysmograph. Static pressure-volume curves were obtained by stepwise interruption of a slow expiration from total lung capacity (TLC) to RV. Static compliance was measured by the slope of pressure-volume curve between functional residual capacity (FRC) and FRC+20% of TLC. Maximum flow static recoil (MFSR) curves were constructed by plotting MEF obtained from MEFV curves against elastic pressure (Pst) obtained from pressure-volume curves at the same lung volumes. Most patients demonstrated a decrease of MEF 50% and 25% of VC. From the MFSR curves it was clear that this reduction was not the result of increased airways resistance, but rather of loss of elastic recoil. Most patients showed a significant decrease of Pst at different volumes and changes seem likely to be evidence of emphysema.</description><subject>Adult</subject><subject>Airway Resistance</subject><subject>Female</subject><subject>Forced Expiratory Volume</subject><subject>Humans</subject><subject>Lung - physiopathology</subject><subject>Lung Compliance</subject><subject>Lung Diseases - physiopathology</subject><subject>Lung Volume Measurements</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Residual Volume</subject><issn>0040-6376</issn><issn>1468-3296</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kb1v1DAYhy1EVY6DjRUpEhIs5PBX7GToAFdaKp1gADp0sWzHaXwkdvFHW_57jO50ogxMHp7H9u99fwC8QHCFEGHv0ni_Is2KrShDj8ACUdbWBHfsMVhASGHNCGdPwNMYtxDCFiF-DI45JZRAsgBXm-yuq9noUTqrY2VdFbPaGp1iFUd_Zwu1Tgcjo-mrYKLts5yqWz_l2VR3No0-p0oF7_RoC_AqppB1st49A0eDnKJ5vj-X4PvZx2_rT_Xmy_nF-v2mVpSzVPcDw9o0cJAScsX6QUkyINwZQ1lHGGWaE9RzhXjfDlxKQjHSLdOdbFmjuoEswcnu3ZusZtNr41KQk7gJdpbhl_DSiofE2VFc-1tBOSJlg0vwen8_-J_ZxCRmG7WZJumMz1HwhpAGY1rEV_-IW5-DK7MJxDnCbYcoLtbbnaWDjzGY4ZAEQfGnMFEKE6QRTJTCiv7y7_QHed9Q4fWO25jM_QHL8EMwTngjPl-uxenlB_z1DF6J0-K_2flq3v7_59-zFbA2</recordid><startdate>19800601</startdate><enddate>19800601</enddate><creator>Vulterini, S</creator><creator>Bianco, M R</creator><creator>Pellicciotti, L</creator><creator>Sidoti, A M</creator><general>BMJ Publishing Group Ltd and British Thoracic Society</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19800601</creationdate><title>Lung mechanics in subjects showing increased residual volume without bronchial obstruction</title><author>Vulterini, S ; Bianco, M R ; Pellicciotti, L ; Sidoti, A M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b476t-df62ce50faa07b6dfba3f129ee4693646c731d7b17d8f7aa3421c86c9a865b9f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Adult</topic><topic>Airway Resistance</topic><topic>Female</topic><topic>Forced Expiratory Volume</topic><topic>Humans</topic><topic>Lung - physiopathology</topic><topic>Lung Compliance</topic><topic>Lung Diseases - physiopathology</topic><topic>Lung Volume Measurements</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Residual Volume</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vulterini, S</creatorcontrib><creatorcontrib>Bianco, M R</creatorcontrib><creatorcontrib>Pellicciotti, L</creatorcontrib><creatorcontrib>Sidoti, A M</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Thorax</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vulterini, S</au><au>Bianco, M R</au><au>Pellicciotti, L</au><au>Sidoti, A M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lung mechanics in subjects showing increased residual volume without bronchial obstruction</atitle><jtitle>Thorax</jtitle><addtitle>Thorax</addtitle><date>1980-06-01</date><risdate>1980</risdate><volume>35</volume><issue>6</issue><spage>461</spage><epage>466</epage><pages>461-466</pages><issn>0040-6376</issn><eissn>1468-3296</eissn><coden>THORA7</coden><abstract>Fourteen subjects showing an increase of residual volume (RV) without any clinical or functional signs of bronchial obstruction were studied. Maximum expiratory flow volume (MEFV) curves were obtained with a pressure-corrected volume plethysmograph. Static pressure-volume curves were obtained by stepwise interruption of a slow expiration from total lung capacity (TLC) to RV. Static compliance was measured by the slope of pressure-volume curve between functional residual capacity (FRC) and FRC+20% of TLC. Maximum flow static recoil (MFSR) curves were constructed by plotting MEF obtained from MEFV curves against elastic pressure (Pst) obtained from pressure-volume curves at the same lung volumes. Most patients demonstrated a decrease of MEF 50% and 25% of VC. From the MFSR curves it was clear that this reduction was not the result of increased airways resistance, but rather of loss of elastic recoil. Most patients showed a significant decrease of Pst at different volumes and changes seem likely to be evidence of emphysema.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and British Thoracic Society</pub><pmid>7434303</pmid><doi>10.1136/thx.35.6.461</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Airway Resistance Female Forced Expiratory Volume Humans Lung - physiopathology Lung Compliance Lung Diseases - physiopathology Lung Volume Measurements Male Middle Aged Residual Volume |
| title | Lung mechanics in subjects showing increased residual volume without bronchial obstruction |
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