Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups

Glioblastoma with oligodendroglioma component (GBM-O) was recognized as a histologic pattern of glioblastoma (GBM) by the World Health Organization (WHO) in 2007 and is distinguished by the presence of oligodendroglioma-like differentiation. To better understand the genetic underpinnings of this mor...

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Veröffentlicht in:	Acta neuropathologica communications 2016-01, Vol.4 (4), p.4-4, Article 4
Hauptverfasser:	Hinrichs, Benjamin H, Newman, Scott, Appin, Christina L, Dunn, William, Cooper, Lee, Pauly, Rini, Kowalski, Jeanne, Rossi, Michael R, Brat, Daniel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Brain Neoplasms - genetics Chromosome Aberrations Chromosomes, Human, Pair 19 - genetics Cyclin-Dependent Kinase Inhibitor p16 - genetics Development and progression Female Gene Expression Gene mutations Genetic aspects Genetic transcription Genomics - methods Glioblastoma - complications Glioblastoma - genetics Glioblastoma multiforme Health aspects Humans Identification and classification Isocitrate Dehydrogenase - genetics Male Microarray Analysis Middle Aged Mutation - genetics Oligodendroglioma - complications Oligodendroglioma - genetics Retrospective Studies Sequence Analysis, DNA Tumor Suppressor Protein p53 - genetics
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