Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration

Zinc finger motifs are distributed amongst many eukaryotic protein families, directing nucleic acid-protein and protein-protein interactions. Zinc finger protein 106 (ZFP106) has previously been associated with roles in immune response, muscle differentiation, testes development and DNA damage, alth...

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Veröffentlicht in:	Human molecular genetics 2016-01, Vol.25 (2), p.291-307
Hauptverfasser:	Joyce, Peter I, Fratta, Pietro, Landman, Allison S, Mcgoldrick, Philip, Wackerhage, Henning, Groves, Michael, Busam, Bharani Shiva, Galino, Jorge, Corrochano, Silvia, Beskina, Olga A, Esapa, Christopher, Ryder, Edward, Carter, Sarah, Stewart, Michelle, Codner, Gemma, Hilton, Helen, Teboul, Lydia, Tucker, Jennifer, Lionikas, Arimantas, Estabel, Jeanne, Ramirez-Solis, Ramiro, White, Jacqueline K, Brandner, Sebastian, Plagnol, Vincent, Bennet, David L H, Abramov, Andrey Y, Greensmith, Linda, Fisher, Elizabeth M C, Acevedo-Arozena, Abraham
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Animals Disease Models, Animal Female Male Mice Mice, Knockout Mitochondria - metabolism Mitochondria - physiology Motor Neurons - metabolism Motor Neurons - physiology Neurodegenerative Diseases - genetics Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - physiopathology Sensory Receptor Cells - metabolism Sensory Receptor Cells - physiology
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