Mouse genome database 2016
The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the rel...
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Veröffentlicht in: | Nucleic acids research 2016-01, Vol.44 (D1), p.D840-D847 |
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container_title | Nucleic acids research |
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creator | Bult, Carol J Eppig, Janan T Blake, Judith A Kadin, James A Richardson, Joel E |
description | The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data. |
doi_str_mv | 10.1093/nar/gkv1211 |
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As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. 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As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data.</description><subject>Alleles</subject><subject>Animals</subject><subject>Database Issue</subject><subject>Databases, Genetic</subject><subject>Disease Models, Animal</subject><subject>Genes</subject><subject>Genome</subject><subject>Mice - genetics</subject><subject>Phenotype</subject><issn>0305-1048</issn><issn>1362-4962</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkMtLw0AQhxdRbK2evHmQHgWJndlXdi9CKb6g4kXPyyTZ1GgeNZsW_O9NaS16Gob5-M3Mx9g5wg2CFZOa2snic40c8YANUWgeSav5IRuCABUhSDNgJyF8AKBEJY_ZgGsVGw0wZBfPzSr48cLXTeXHGXWUUN9zQH3KjnIqgz_b1RF7u797nT1G85eHp9l0HqXCYBfl4HUGpDmXWS7QkpWWowFUmeVkcmW4idNEJ5KTolgnhDrJyKQA0goQYsRut7nLVVL5LPV111Lplm1RUfvtGirc_0ldvLtFs3YyBt5_0Qdc7QLa5mvlQ-eqIqS-LKn2_XcOYw1Go1Ab9HqLpm0TQuvz_RoEt7HpeptuZ7OnL_9etmd_9Ykf2bdu5A</recordid><startdate>20160104</startdate><enddate>20160104</enddate><creator>Bult, Carol J</creator><creator>Eppig, Janan T</creator><creator>Blake, Judith A</creator><creator>Kadin, James A</creator><creator>Richardson, Joel E</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160104</creationdate><title>Mouse genome database 2016</title><author>Bult, Carol J ; Eppig, Janan T ; Blake, Judith A ; Kadin, James A ; Richardson, Joel E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-f0e6d0a6224df319a949218015d92a8f58287cb6b42a5a76ba16bda8c00493033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Alleles</topic><topic>Animals</topic><topic>Database Issue</topic><topic>Databases, Genetic</topic><topic>Disease Models, Animal</topic><topic>Genes</topic><topic>Genome</topic><topic>Mice - genetics</topic><topic>Phenotype</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bult, Carol J</creatorcontrib><creatorcontrib>Eppig, Janan T</creatorcontrib><creatorcontrib>Blake, Judith A</creatorcontrib><creatorcontrib>Kadin, James A</creatorcontrib><creatorcontrib>Richardson, Joel E</creatorcontrib><creatorcontrib>Mouse Genome Database Group</creatorcontrib><creatorcontrib>the Mouse Genome Database Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nucleic acids research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bult, Carol J</au><au>Eppig, Janan T</au><au>Blake, Judith A</au><au>Kadin, James A</au><au>Richardson, Joel E</au><aucorp>Mouse Genome Database Group</aucorp><aucorp>the Mouse Genome Database Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mouse genome database 2016</atitle><jtitle>Nucleic acids research</jtitle><addtitle>Nucleic Acids Res</addtitle><date>2016-01-04</date><risdate>2016</risdate><volume>44</volume><issue>D1</issue><spage>D840</spage><epage>D847</epage><pages>D840-D847</pages><issn>0305-1048</issn><eissn>1362-4962</eissn><abstract>The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>26578600</pmid><doi>10.1093/nar/gkv1211</doi><oa>free_for_read</oa></addata></record> |
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language | eng |
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source | Oxford Journals Open Access Collection; MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central; Free Full-Text Journals in Chemistry |
subjects | Alleles Animals Database Issue Databases, Genetic Disease Models, Animal Genes Genome Mice - genetics Phenotype |
title | Mouse genome database 2016 |
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