Presence of unique glyoxalase III proteins in plants indicates the existence of shorter route for methylglyoxal detoxification

Glyoxalase pathway, comprising glyoxalase I (GLY I) and glyoxalase II (GLY II) enzymes, is the major pathway for detoxification of methylglyoxal (MG) into D-lactate involving reduced glutathione (GSH). However, in bacteria, glyoxalase III (GLY III) with DJ-1/PfpI domain(s) can do the same conversion...

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Veröffentlicht in:	Scientific reports 2016-01, Vol.6 (1), p.18358, Article 18358
Hauptverfasser:	Ghosh, Ajit, Kushwaha, Hemant R, Hasan, Mohammad R, Pareek, Ashwani, Sopory, Sudhir K, Singla-Pareek, Sneh L
Format:	Artikel
Sprache:	eng
Schlagworte:	38/39 38/77 38/90 45 631/449/2661/2665 631/45/173 82 82/80 82/83 96 Alanine Aldehyde Oxidoreductases - chemistry Aldehyde Oxidoreductases - metabolism Amino Acid Sequence Aquatic plants Catalytic Domain Chromosome Mapping Detoxification Developmental stages Enzymes Gene Expression Profiling Gene Expression Regulation, Plant Genome, Plant Genomes Glutathione Humanities and Social Sciences Hydroxyacylglutathione hydrolase Inactivation, Metabolic Lactic acid Lactoylglutathione lyase Localization Metabolic Networks and Pathways multidisciplinary Mutation Organ Specificity - genetics Oryza - classification Oryza - genetics Oryza - metabolism PARK7 protein Phylogeny Plant Proteins - chemistry Plant Proteins - metabolism Plants - classification Plants - genetics Plants - metabolism Promoter Regions, Genetic Protein Interaction Domains and Motifs Proteins Pyruvaldehyde Pyruvaldehyde - metabolism Response Elements Science Site-directed mutagenesis Stress, Physiological Transcription
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