Network-Based Approaches in Drug Discovery and Early Development

Identification of novel targets is a critical first step in the drug discovery and development process. Most diseases such as cancer, metabolic disorders, and neurological disorders are complex, and their pathogenesis involves multiple genetic and environmental factors. Finding a viable drug target–...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2013-12, Vol.94 (6), p.651-658
Hauptverfasser:	Harrold, J M, Ramanathan, M, Mager, D E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Computational Biology - methods Databases, Genetic Drug Discovery - methods Gene Regulatory Networks Humans Medical sciences Metabolic Networks and Pathways Models, Biological Molecular Targeted Therapy Pharmacology. Drug treatments Precision Medicine - methods Signal Transduction Systems Biology
Online-Zugang:	Volltext
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