Local compartment changes and regulatory landscape alterations in histone H1-depleted cells

Linker histone H1 is a core chromatin component that binds to nucleosome core particles and the linker DNA between nucleosomes. It has been implicated in chromatin compaction and gene regulation and is anticipated to play a role in higher-order genome structure. Here we have used a combination of ge...

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Veröffentlicht in:	Genome Biology 2015-12, Vol.16 (290), p.289-289, Article 289
Hauptverfasser:	Geeven, Geert, Zhu, Yun, Kim, Byung Ju, Bartholdy, Boris A, Yang, Seung-Min, Macfarlan, Todd S, Gifford, Wesley D, Pfaff, Samuel L, Verstegen, Marjon J A M, Pinto, Hugo, Vermunt, Marit W, Creyghton, Menno P, Wijchers, Patrick J, Stamatoyannopoulos, John A, Skoultchi, Arthur I, de Laat, Wouter
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Bioinformatics Cell Line Chromatin Chromatin - genetics Chromatin - metabolism Chromatin Assembly and Disassembly Chromosomes Core particles Deoxyribonuclease Deoxyribonucleic acid DNA DNA methylation Embryo cells Embryonic stem cells Epigenesis, Genetic Epigenetic inheritance Gene expression Gene regulation Genomes Histone H1 Histones - genetics Histones - metabolism Methylation Mice Nucleases Nucleosomes Physiological aspects RNA polymerase Segmentation Software Stem cells Transcription
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