Interactive effects of cerium oxide and diesel exhaust nanoparticles on inducing pulmonary fibrosis

Cerium compounds have been used as a fuel-borne catalyst to lower the generation of diesel exhaust particles (DEPs), but are emitted as cerium oxide nanoparticles (CeO2) along with DEP in the diesel exhaust. The present study investigates the effects of the combined exposure to DEP and CeO2 on the p...

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Veröffentlicht in:	Toxicology and applied pharmacology 2014-07, Vol.278 (2), p.135-147
Hauptverfasser:	Ma, Jane Y.C., Young, Shih-Houng, Mercer, Robert R., Barger, Mark, Schwegler-Berry, Diane, Ma, Joseph K., Castranova, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Animals ARGINASE Biological and medical sciences CATALYSTS Cerium - analysis Cerium - toxicity Cerium oxide CERIUM OXIDES COLLAGEN CONCANAVALIN A Cross-disciplinary physics: materials science rheology Diesel exhaust particles DIESEL FUELS Drug Interactions Exact sciences and technology FIBROSIS GRANULOMAS INFLAMMATION Inhalation Exposure - adverse effects Lung fibrosis LUNGS LYMPH NODES Lymphatic system LYMPHOCYTES LYMPHOKINES MACROPHAGES Male Materials science Medical sciences Nanoparticle NANOPARTICLES Nanoparticles - analysis Nanoparticles - toxicity Nanoscale materials and structures: fabrication and characterization Particulate Matter - analysis Particulate Matter - toxicity PATHOGENS PHOSPHOLIPIDS Physics Pneumology Pulmonary Fibrosis - chemically induced Pulmonary Fibrosis - pathology Pulmonary inflammation RATS Rats, Sprague-Dawley Respiratory system : syndromes and miscellaneous diseases SECRETION Toxicology TRANSMISSION ELECTRON MICROSCOPY Vehicle Emissions - analysis Vehicle Emissions - toxicity
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