Phasic dopamine signals: from subjective reward value to formal economic utility

•Dopamine neurons code subjective value of different rewards according to behavioral choices.•Dopamine neuronal and voltammetry responses follow individual risk preferences.•Dopamine neuronal and voltammetry responses follow temporal reward discounting.•Dopamine voltammetry responses are sensitive t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Current opinion in behavioral sciences 2015-10, Vol.5, p.147-154
Hauptverfasser: Schultz, Wolfram, Carelli, Regina M, Wightman, R Mark
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 154
container_issue
container_start_page 147
container_title Current opinion in behavioral sciences
container_volume 5
creator Schultz, Wolfram
Carelli, Regina M
Wightman, R Mark
description •Dopamine neurons code subjective value of different rewards according to behavioral choices.•Dopamine neuronal and voltammetry responses follow individual risk preferences.•Dopamine neuronal and voltammetry responses follow temporal reward discounting.•Dopamine voltammetry responses are sensitive to effort cost.•Dopamine neuronal responses code formal economic utility. Although rewards are physical stimuli and objects, their value for survival and reproduction is subjective. The phasic, neurophysiological and voltammetric dopamine reward prediction error response signals subjective reward value. The signal incorporates crucial reward aspects such as amount, probability, type, risk, delay and effort. Differences of dopamine release dynamics with temporal delay and effort in rodents may derive from methodological issues and require further study. Recent designs using concepts and behavioral tools from experimental economics allow to formally characterize the subjective value signal as economic utility and thus to establish a neuronal value function. With these properties, the dopamine response constitutes a utility prediction error signal.
doi_str_mv 10.1016/j.cobeha.2015.09.006
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4692271</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S2352154615001229</els_id><sourcerecordid>1826648064</sourcerecordid><originalsourceid>FETCH-LOGICAL-c599t-7bc4b64f707df22182d62adcadf66d0f4e472ef77cf0830624f3acbc2ce6ef593</originalsourceid><addsrcrecordid>eNp9UU1LxDAQDaKoqP9AJEcvW5M0TbYeBBG_QNCDnkOaTNwsbbMm7cr-eyOrq148zcDMe_PmPYSOKSkooeJsXpjQwEwXjNCqIHVBiNhC-6ys2IRWFd_e9FzsoaOU5oQQWkpRyXoX7TEhaT2tyn309DTTyRtsw0J3vgec_Guv23SOXQwdTmMzBzP4JeAI7zpavNTtCHgI2IXY6RaDCX3oMsM4-NYPq0O04zIejr7qAXq5uX6-ups8PN7eX10-TExV18NENoY3gjtJpHWM0SmzgmlrtHVCWOI4cMnASWkcmZZEMO5KbRrDDAhwVV0eoIs172JsOrAG-iHqVi2i73RcqaC9-jvp_Uy9hqXiomZM0kxw-kUQw9sIaVCdTwbaVvcQxqSyJCH4lAieV_l61cSQUgS3OUOJ-sxDzdU6D_WZhyK1ynlk2MlviRvQt_s_P0A2aukhqmQ89Aasj9l1ZYP__8IHcMCgSA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1826648064</pqid></control><display><type>article</type><title>Phasic dopamine signals: from subjective reward value to formal economic utility</title><source>Alma/SFX Local Collection</source><creator>Schultz, Wolfram ; Carelli, Regina M ; Wightman, R Mark</creator><creatorcontrib>Schultz, Wolfram ; Carelli, Regina M ; Wightman, R Mark</creatorcontrib><description>•Dopamine neurons code subjective value of different rewards according to behavioral choices.•Dopamine neuronal and voltammetry responses follow individual risk preferences.•Dopamine neuronal and voltammetry responses follow temporal reward discounting.•Dopamine voltammetry responses are sensitive to effort cost.•Dopamine neuronal responses code formal economic utility. Although rewards are physical stimuli and objects, their value for survival and reproduction is subjective. The phasic, neurophysiological and voltammetric dopamine reward prediction error response signals subjective reward value. The signal incorporates crucial reward aspects such as amount, probability, type, risk, delay and effort. Differences of dopamine release dynamics with temporal delay and effort in rodents may derive from methodological issues and require further study. Recent designs using concepts and behavioral tools from experimental economics allow to formally characterize the subjective value signal as economic utility and thus to establish a neuronal value function. With these properties, the dopamine response constitutes a utility prediction error signal.</description><identifier>ISSN: 2352-1546</identifier><identifier>EISSN: 2352-1554</identifier><identifier>DOI: 10.1016/j.cobeha.2015.09.006</identifier><identifier>PMID: 26719853</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><ispartof>Current opinion in behavioral sciences, 2015-10, Vol.5, p.147-154</ispartof><rights>2015 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c599t-7bc4b64f707df22182d62adcadf66d0f4e472ef77cf0830624f3acbc2ce6ef593</citedby><cites>FETCH-LOGICAL-c599t-7bc4b64f707df22182d62adcadf66d0f4e472ef77cf0830624f3acbc2ce6ef593</cites><orcidid>0000-0003-2198-139X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,782,786,887,27931,27932</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26719853$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schultz, Wolfram</creatorcontrib><creatorcontrib>Carelli, Regina M</creatorcontrib><creatorcontrib>Wightman, R Mark</creatorcontrib><title>Phasic dopamine signals: from subjective reward value to formal economic utility</title><title>Current opinion in behavioral sciences</title><addtitle>Curr Opin Behav Sci</addtitle><description>•Dopamine neurons code subjective value of different rewards according to behavioral choices.•Dopamine neuronal and voltammetry responses follow individual risk preferences.•Dopamine neuronal and voltammetry responses follow temporal reward discounting.•Dopamine voltammetry responses are sensitive to effort cost.•Dopamine neuronal responses code formal economic utility. Although rewards are physical stimuli and objects, their value for survival and reproduction is subjective. The phasic, neurophysiological and voltammetric dopamine reward prediction error response signals subjective reward value. The signal incorporates crucial reward aspects such as amount, probability, type, risk, delay and effort. Differences of dopamine release dynamics with temporal delay and effort in rodents may derive from methodological issues and require further study. Recent designs using concepts and behavioral tools from experimental economics allow to formally characterize the subjective value signal as economic utility and thus to establish a neuronal value function. With these properties, the dopamine response constitutes a utility prediction error signal.</description><issn>2352-1546</issn><issn>2352-1554</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9UU1LxDAQDaKoqP9AJEcvW5M0TbYeBBG_QNCDnkOaTNwsbbMm7cr-eyOrq148zcDMe_PmPYSOKSkooeJsXpjQwEwXjNCqIHVBiNhC-6ys2IRWFd_e9FzsoaOU5oQQWkpRyXoX7TEhaT2tyn309DTTyRtsw0J3vgec_Guv23SOXQwdTmMzBzP4JeAI7zpavNTtCHgI2IXY6RaDCX3oMsM4-NYPq0O04zIejr7qAXq5uX6-ups8PN7eX10-TExV18NENoY3gjtJpHWM0SmzgmlrtHVCWOI4cMnASWkcmZZEMO5KbRrDDAhwVV0eoIs172JsOrAG-iHqVi2i73RcqaC9-jvp_Uy9hqXiomZM0kxw-kUQw9sIaVCdTwbaVvcQxqSyJCH4lAieV_l61cSQUgS3OUOJ-sxDzdU6D_WZhyK1ynlk2MlviRvQt_s_P0A2aukhqmQ89Aasj9l1ZYP__8IHcMCgSA</recordid><startdate>20151001</startdate><enddate>20151001</enddate><creator>Schultz, Wolfram</creator><creator>Carelli, Regina M</creator><creator>Wightman, R Mark</creator><general>Elsevier Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2198-139X</orcidid></search><sort><creationdate>20151001</creationdate><title>Phasic dopamine signals: from subjective reward value to formal economic utility</title><author>Schultz, Wolfram ; Carelli, Regina M ; Wightman, R Mark</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c599t-7bc4b64f707df22182d62adcadf66d0f4e472ef77cf0830624f3acbc2ce6ef593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schultz, Wolfram</creatorcontrib><creatorcontrib>Carelli, Regina M</creatorcontrib><creatorcontrib>Wightman, R Mark</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Current opinion in behavioral sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schultz, Wolfram</au><au>Carelli, Regina M</au><au>Wightman, R Mark</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phasic dopamine signals: from subjective reward value to formal economic utility</atitle><jtitle>Current opinion in behavioral sciences</jtitle><addtitle>Curr Opin Behav Sci</addtitle><date>2015-10-01</date><risdate>2015</risdate><volume>5</volume><spage>147</spage><epage>154</epage><pages>147-154</pages><issn>2352-1546</issn><eissn>2352-1554</eissn><abstract>•Dopamine neurons code subjective value of different rewards according to behavioral choices.•Dopamine neuronal and voltammetry responses follow individual risk preferences.•Dopamine neuronal and voltammetry responses follow temporal reward discounting.•Dopamine voltammetry responses are sensitive to effort cost.•Dopamine neuronal responses code formal economic utility. Although rewards are physical stimuli and objects, their value for survival and reproduction is subjective. The phasic, neurophysiological and voltammetric dopamine reward prediction error response signals subjective reward value. The signal incorporates crucial reward aspects such as amount, probability, type, risk, delay and effort. Differences of dopamine release dynamics with temporal delay and effort in rodents may derive from methodological issues and require further study. Recent designs using concepts and behavioral tools from experimental economics allow to formally characterize the subjective value signal as economic utility and thus to establish a neuronal value function. With these properties, the dopamine response constitutes a utility prediction error signal.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>26719853</pmid><doi>10.1016/j.cobeha.2015.09.006</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-2198-139X</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2352-1546
ispartof Current opinion in behavioral sciences, 2015-10, Vol.5, p.147-154
issn 2352-1546
2352-1554
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4692271
source Alma/SFX Local Collection
title Phasic dopamine signals: from subjective reward value to formal economic utility
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-05T14%3A00%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Phasic%20dopamine%20signals:%20from%20subjective%20reward%20value%20to%20formal%20economic%20utility&rft.jtitle=Current%20opinion%20in%20behavioral%20sciences&rft.au=Schultz,%20Wolfram&rft.date=2015-10-01&rft.volume=5&rft.spage=147&rft.epage=154&rft.pages=147-154&rft.issn=2352-1546&rft.eissn=2352-1554&rft_id=info:doi/10.1016/j.cobeha.2015.09.006&rft_dat=%3Cproquest_pubme%3E1826648064%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1826648064&rft_id=info:pmid/26719853&rft_els_id=S2352154615001229&rfr_iscdi=true