Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II

Background. Rapid molecular diagnostic (RMD) platforms may lead to better antibiotic use. Our objective was to develop analytical strategies to enhance the interpretation of RMDs for clinicians. Methods. We compared the performance characteristics of 4 RMD platforms for detecting resistance against...

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Veröffentlicht in:	Clinical infectious diseases 2016-01, Vol.62 (2), p.181-189
Hauptverfasser:	Evans, Scott R., Hujer, Andrea M., Jiang, Hongyu, Hujer, Kristine M., Hall, Thomas, Marzan, Christine, Jacobs, Michael R., Sampath, Rangarajan, Ecker, David J., Manca, Claudia, Chavda, Kalyan, Zhang, Pan, Fernandez, Helen, Chen, Liang, Mediavilla, Jose R., Hill, Carol B., Perez, Federico, Caliendo, Angela M., Fowler, Vance G., Chambers, Henry F., Kreiswirth, Barry N., Bonomo, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	and Commentaries Anti-Bacterial Agents - therapeutic use Antibiotics ARTICLES AND COMMENTARIES Bacterial infections beta-Lactam Resistance Decision making Drug resistance Drug therapy Enterobacteriaceae Infections - drug therapy Enterobacteriaceae Infections - microbiology Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - isolation & purification Genes Genotyping Techniques - methods Humans Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - genetics Klebsiella pneumoniae - isolation & purification Medical diagnosis Microbial Sensitivity Tests - methods Molecular Diagnostic Techniques - methods Time Factors
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