Intermediate-term trends in serum levels of metal ions after hip resurfacing arthroplasty
The potential risks associated with hip resurfacing arthroplasty (HRA) are controversial and underestimated. The aim of this study was to explore intermediate-term trends for the levels of cobalt (Co), chromium (Cr), and molybdenum (Mo) ions after HRA. Forty patients who underwent HRA from October 2...
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| Veröffentlicht in: | Journal of orthopaedic surgery and research 2015-12, Vol.10 (188), p.188-188, Article 188 |
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| creator | Jiang, Wenxue Wan, Yanlin Cui, Peng Ning, Xianjia |
| description | The potential risks associated with hip resurfacing arthroplasty (HRA) are controversial and underestimated. The aim of this study was to explore intermediate-term trends for the levels of cobalt (Co), chromium (Cr), and molybdenum (Mo) ions after HRA.
Forty patients who underwent HRA from October 2005 to December 2010 were recruited to this study. The serum levels of metal ions were examined preoperatively and 3, 12, 24, and 60 months after surgery. Trends and differences in levels of metal ions with respect to sex, operated side, and body mass index (BMI) were analyzed.
There were no significant differences in levels of Cr, Co, and Mo at each time point with respect to sex, operated side, and BMI (p > 0.05). The postoperative levels of Cr, Co, and Mo ions were significantly higher than the preoperative levels across sex, operated side, and BMI groups. Postoperative levels of Cr, Co, and Mo peaked at 12, 24, and 60 months, respectively. Cr levels peaked earlier (at 12 months) in the overweight (BMI ≥25 kg/m(2)) group compared to the normal-weight group (BMI |
| doi_str_mv | 10.1186/s13018-015-0335-0 |
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Forty patients who underwent HRA from October 2005 to December 2010 were recruited to this study. The serum levels of metal ions were examined preoperatively and 3, 12, 24, and 60 months after surgery. Trends and differences in levels of metal ions with respect to sex, operated side, and body mass index (BMI) were analyzed.
There were no significant differences in levels of Cr, Co, and Mo at each time point with respect to sex, operated side, and BMI (p > 0.05). The postoperative levels of Cr, Co, and Mo ions were significantly higher than the preoperative levels across sex, operated side, and BMI groups. Postoperative levels of Cr, Co, and Mo peaked at 12, 24, and 60 months, respectively. Cr levels peaked earlier (at 12 months) in the overweight (BMI ≥25 kg/m(2)) group compared to the normal-weight group (BMI <25 kg/m(2)), Co levels (at 12 months) peaked in women compared to men, and Mo levels (at 3 months) peaked in the bilateral HRA group compared to the unilateral HRA group.
Serum levels of Cr, Co, and Mo increased significantly after HRA. Cr levels peaked earlier in the overweight patients, Co levels peaked in women, and Mo levels peaked in patients who underwent bilateral HRA. However, there were no significant differences with respect to sex, operated side, and BMI.</description><identifier>ISSN: 1749-799X</identifier><identifier>EISSN: 1749-799X</identifier><identifier>DOI: 10.1186/s13018-015-0335-0</identifier><identifier>PMID: 26698115</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adult ; Analysis ; Arthroplasty, Replacement, Hip - trends ; Biomarkers - blood ; Body mass index ; Chromium - blood ; Cobalt - blood ; Female ; Follow-Up Studies ; Hip Prosthesis - trends ; Humans ; Ions ; Male ; Metal ions ; Metals - blood ; Middle Aged ; Molybdenum - blood ; Orthopedics ; Postoperative Care - trends</subject><ispartof>Journal of orthopaedic surgery and research, 2015-12, Vol.10 (188), p.188-188, Article 188</ispartof><rights>COPYRIGHT 2015 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2015</rights><rights>Jiang et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c564t-a243e24e6104838cc20f30f5db3a43cd0b66d769681959e5850a22bb2e7d0ce33</citedby><cites>FETCH-LOGICAL-c564t-a243e24e6104838cc20f30f5db3a43cd0b66d769681959e5850a22bb2e7d0ce33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690317/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690317/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26698115$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jiang, Wenxue</creatorcontrib><creatorcontrib>Wan, Yanlin</creatorcontrib><creatorcontrib>Cui, Peng</creatorcontrib><creatorcontrib>Ning, Xianjia</creatorcontrib><title>Intermediate-term trends in serum levels of metal ions after hip resurfacing arthroplasty</title><title>Journal of orthopaedic surgery and research</title><addtitle>J Orthop Surg Res</addtitle><description>The potential risks associated with hip resurfacing arthroplasty (HRA) are controversial and underestimated. The aim of this study was to explore intermediate-term trends for the levels of cobalt (Co), chromium (Cr), and molybdenum (Mo) ions after HRA.
Forty patients who underwent HRA from October 2005 to December 2010 were recruited to this study. The serum levels of metal ions were examined preoperatively and 3, 12, 24, and 60 months after surgery. Trends and differences in levels of metal ions with respect to sex, operated side, and body mass index (BMI) were analyzed.
There were no significant differences in levels of Cr, Co, and Mo at each time point with respect to sex, operated side, and BMI (p > 0.05). The postoperative levels of Cr, Co, and Mo ions were significantly higher than the preoperative levels across sex, operated side, and BMI groups. Postoperative levels of Cr, Co, and Mo peaked at 12, 24, and 60 months, respectively. Cr levels peaked earlier (at 12 months) in the overweight (BMI ≥25 kg/m(2)) group compared to the normal-weight group (BMI <25 kg/m(2)), Co levels (at 12 months) peaked in women compared to men, and Mo levels (at 3 months) peaked in the bilateral HRA group compared to the unilateral HRA group.
Serum levels of Cr, Co, and Mo increased significantly after HRA. Cr levels peaked earlier in the overweight patients, Co levels peaked in women, and Mo levels peaked in patients who underwent bilateral HRA. However, there were no significant differences with respect to sex, operated side, and BMI.</description><subject>Adult</subject><subject>Analysis</subject><subject>Arthroplasty, Replacement, Hip - trends</subject><subject>Biomarkers - blood</subject><subject>Body mass index</subject><subject>Chromium - blood</subject><subject>Cobalt - blood</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hip Prosthesis - trends</subject><subject>Humans</subject><subject>Ions</subject><subject>Male</subject><subject>Metal ions</subject><subject>Metals - blood</subject><subject>Middle Aged</subject><subject>Molybdenum - blood</subject><subject>Orthopedics</subject><subject>Postoperative Care - trends</subject><issn>1749-799X</issn><issn>1749-799X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNptkk1rHSEUhqW0NOltf0A3Reimm0l1_BhnUwihH4FANy20K3Gc470GR2_VCeTf18tN06QU4XjQ57x69EXoNSVnlCr5vlBGqOoIFR1hrIUn6JQOfOyGcfzx9EF-gl6Uck2IIELx5-ikl3JUlIpT9PMyVsgLzN5U6A4prhniXLCPuEBeFxzgBkLByeEFqgnYp1iwcY3FO7_HGcqanbE-brHJdZfTPphSb1-iZ86EAq_u5g36_unjt4sv3dXXz5cX51edFZLXzvScQc9BUsIVU9b2xDHixDwxw5mdySTlPMhRKjqKEYQSxPT9NPUwzMQCYxv04ai7X6fWh4VYswl6n_1i8q1OxuvHO9Hv9DbdaC5HwujQBN7dCeT0a4VS9eKLhRBMhLQWTQfRM0GFog19-w96ndYcW3uNGtod2y8Mf6mtCaB9dKmdaw-i-pwL2t6eK9Gos_9QbcyweJsiON_WHxXQY4HNqZQM7r5HSvTBD_roB938oA9-aGGD3jx8nPuKPwZgvwEBXLCQ</recordid><startdate>20151223</startdate><enddate>20151223</enddate><creator>Jiang, Wenxue</creator><creator>Wan, Yanlin</creator><creator>Cui, Peng</creator><creator>Ning, Xianjia</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20151223</creationdate><title>Intermediate-term trends in serum levels of metal ions after hip resurfacing arthroplasty</title><author>Jiang, Wenxue ; Wan, Yanlin ; Cui, Peng ; Ning, Xianjia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c564t-a243e24e6104838cc20f30f5db3a43cd0b66d769681959e5850a22bb2e7d0ce33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Analysis</topic><topic>Arthroplasty, Replacement, Hip - trends</topic><topic>Biomarkers - blood</topic><topic>Body mass index</topic><topic>Chromium - blood</topic><topic>Cobalt - blood</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hip Prosthesis - trends</topic><topic>Humans</topic><topic>Ions</topic><topic>Male</topic><topic>Metal ions</topic><topic>Metals - blood</topic><topic>Middle Aged</topic><topic>Molybdenum - blood</topic><topic>Orthopedics</topic><topic>Postoperative Care - trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jiang, Wenxue</creatorcontrib><creatorcontrib>Wan, Yanlin</creatorcontrib><creatorcontrib>Cui, Peng</creatorcontrib><creatorcontrib>Ning, Xianjia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of orthopaedic surgery and research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jiang, Wenxue</au><au>Wan, Yanlin</au><au>Cui, Peng</au><au>Ning, Xianjia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intermediate-term trends in serum levels of metal ions after hip resurfacing arthroplasty</atitle><jtitle>Journal of orthopaedic surgery and research</jtitle><addtitle>J Orthop Surg Res</addtitle><date>2015-12-23</date><risdate>2015</risdate><volume>10</volume><issue>188</issue><spage>188</spage><epage>188</epage><pages>188-188</pages><artnum>188</artnum><issn>1749-799X</issn><eissn>1749-799X</eissn><abstract>The potential risks associated with hip resurfacing arthroplasty (HRA) are controversial and underestimated. The aim of this study was to explore intermediate-term trends for the levels of cobalt (Co), chromium (Cr), and molybdenum (Mo) ions after HRA.
Forty patients who underwent HRA from October 2005 to December 2010 were recruited to this study. The serum levels of metal ions were examined preoperatively and 3, 12, 24, and 60 months after surgery. Trends and differences in levels of metal ions with respect to sex, operated side, and body mass index (BMI) were analyzed.
There were no significant differences in levels of Cr, Co, and Mo at each time point with respect to sex, operated side, and BMI (p > 0.05). The postoperative levels of Cr, Co, and Mo ions were significantly higher than the preoperative levels across sex, operated side, and BMI groups. Postoperative levels of Cr, Co, and Mo peaked at 12, 24, and 60 months, respectively. Cr levels peaked earlier (at 12 months) in the overweight (BMI ≥25 kg/m(2)) group compared to the normal-weight group (BMI <25 kg/m(2)), Co levels (at 12 months) peaked in women compared to men, and Mo levels (at 3 months) peaked in the bilateral HRA group compared to the unilateral HRA group.
Serum levels of Cr, Co, and Mo increased significantly after HRA. Cr levels peaked earlier in the overweight patients, Co levels peaked in women, and Mo levels peaked in patients who underwent bilateral HRA. However, there were no significant differences with respect to sex, operated side, and BMI.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>26698115</pmid><doi>10.1186/s13018-015-0335-0</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Analysis Arthroplasty, Replacement, Hip - trends Biomarkers - blood Body mass index Chromium - blood Cobalt - blood Female Follow-Up Studies Hip Prosthesis - trends Humans Ions Male Metal ions Metals - blood Middle Aged Molybdenum - blood Orthopedics Postoperative Care - trends |
| title | Intermediate-term trends in serum levels of metal ions after hip resurfacing arthroplasty |
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