MTA1-upregulated EpCAM is associated with metastatic behaviors and poor prognosis in lung cancer

Overexpression of Metastasis-associated protein 1 (MTA1) in various cancer cells promotes tumor invasion and migration and predicts cancer patients' poor prognosis. The pilot RNA-Seq data from our laboratory indicated that Epithelial cell adhesion molecule (EpCAM) was statistically reduced in M...

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Veröffentlicht in:	Journal of experimental & clinical cancer research 2015-12, Vol.34 (156), p.157-157, Article 157
Hauptverfasser:	Zhou, Ning, Wang, Haijuan, Liu, Hongxu, Xue, Hongsheng, Lin, Feng, Meng, Xiting, Liang, Ailing, Zhao, Zhilong, Liu, YongJun, Qian, Haili
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Antigens, Neoplasm - biosynthesis Antigens, Neoplasm - genetics Care and treatment Cell Adhesion Molecules - biosynthesis Cell Adhesion Molecules - genetics Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Complications and side effects Epithelial Cell Adhesion Molecule Female Gene Expression Regulation, Neoplastic Histone Deacetylases - biosynthesis Histone Deacetylases - genetics Humans Immunohistochemistry Lung cancer Lung Neoplasms - genetics Lung Neoplasms - pathology Lymphatic Metastasis Male Metastasis Middle Aged Neoplasm Invasiveness - genetics Prognosis Repressor Proteins - antagonists & inhibitors Repressor Proteins - biosynthesis Repressor Proteins - genetics Risk factors RNA sequencing Trans-Activators
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