A prospective, multi-centre, observational study to examine kidney disease progression in adults with chronic kidney disease - CKDOD - Study design and preliminary results
The objective of this article is to describe the organisation of an international, clinical registry, the Chronic Kidney Disease Observational Database (CKDOD), the processes of enrolling patients and entering data and preliminary results to date. The Chronic Kidney Disease Observational Database (C...
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creator | Shah, Bharat Kirpalani, Ashok Sunder, Sham Gupta, Ashwani Khanna, Umesh Chafekar, Deodatta Tan, Li Ping Sirivongs, Dhavee Pahari, Dilip Nath, Gokul Ikizler, Talat Alp |
description | The objective of this article is to describe the organisation of an international, clinical registry, the Chronic Kidney Disease Observational Database (CKDOD), the processes of enrolling patients and entering data and preliminary results to date.
The Chronic Kidney Disease Observational Database (CKDOD) is designed to assess the association between different factors with a known influence on chronic kidney disease (CKD) progression as well as treatment strategies such as dietary modifications, blood pressure control and pharmacological interventions in Asian countries (India, China, Malaysia and Thailand). The only inclusion criterion is the presence of CKD stage 2 or higher as defined by the KDIGO guidelines. Demographic and clinical information are collected by a standardised electronic questionnaire, available in English and Chinese. The data are transferred to the CKDOD database either by e-mail or via web access. All data are checked for consistency and missing values. Collection of data started in September 2011 and by April 2015, data on 1323 individual patients had been submitted. The mean age at inclusion was 57 ± 14 years, 67 % were male and 36 % were diabetic. The baseline estimated glomerular filtration rate was 26 ml/min/1.73 m(2). Of all enrolled patients, 324 (24 %) received ketoanalogue supplementation during at least one recorded visit.
The CKDOD is a very large and comprehensive data repository, currently focused in subjects recruited from Asia. The database is expected to provide important long-term information on CKD progression, nutritional and metabolic derangements that accompany CKD progression and treatment strategies to ameliorate progression and complications of CKD.
Clinical Trial Registry - India: CTRI/2012/06/002743 ; 25th July 2012. |
doi_str_mv | 10.1186/s12882-015-0191-5 |
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The Chronic Kidney Disease Observational Database (CKDOD) is designed to assess the association between different factors with a known influence on chronic kidney disease (CKD) progression as well as treatment strategies such as dietary modifications, blood pressure control and pharmacological interventions in Asian countries (India, China, Malaysia and Thailand). The only inclusion criterion is the presence of CKD stage 2 or higher as defined by the KDIGO guidelines. Demographic and clinical information are collected by a standardised electronic questionnaire, available in English and Chinese. The data are transferred to the CKDOD database either by e-mail or via web access. All data are checked for consistency and missing values. Collection of data started in September 2011 and by April 2015, data on 1323 individual patients had been submitted. The mean age at inclusion was 57 ± 14 years, 67 % were male and 36 % were diabetic. The baseline estimated glomerular filtration rate was 26 ml/min/1.73 m(2). Of all enrolled patients, 324 (24 %) received ketoanalogue supplementation during at least one recorded visit.
The CKDOD is a very large and comprehensive data repository, currently focused in subjects recruited from Asia. The database is expected to provide important long-term information on CKD progression, nutritional and metabolic derangements that accompany CKD progression and treatment strategies to ameliorate progression and complications of CKD.
Clinical Trial Registry - India: CTRI/2012/06/002743 ; 25th July 2012.</description><identifier>ISSN: 1471-2369</identifier><identifier>EISSN: 1471-2369</identifier><identifier>DOI: 10.1186/s12882-015-0191-5</identifier><identifier>PMID: 26696239</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adolescent ; Adult ; Adults ; Aged ; Aged, 80 and over ; Care and treatment ; Chronic kidney failure ; Complications and side effects ; Databases, Factual ; Development and progression ; Disease Progression ; Female ; Health aspects ; Humans ; Male ; Middle Aged ; Morbidity ; Nephrology ; Prospective Studies ; Renal Insufficiency, Chronic - complications ; Research Design ; Risk factors ; Study Protocol ; Young Adult</subject><ispartof>BMC nephrology, 2015-12, Vol.16 (206), p.215-215, Article 215</ispartof><rights>COPYRIGHT 2015 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2015</rights><rights>Shah et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-e6f448f55a51fea0bd77ddff9e710102c7b609d523a594b3f6007ba1404837d53</citedby><cites>FETCH-LOGICAL-c494t-e6f448f55a51fea0bd77ddff9e710102c7b609d523a594b3f6007ba1404837d53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687357/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687357/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26696239$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shah, Bharat</creatorcontrib><creatorcontrib>Kirpalani, Ashok</creatorcontrib><creatorcontrib>Sunder, Sham</creatorcontrib><creatorcontrib>Gupta, Ashwani</creatorcontrib><creatorcontrib>Khanna, Umesh</creatorcontrib><creatorcontrib>Chafekar, Deodatta</creatorcontrib><creatorcontrib>Tan, Li Ping</creatorcontrib><creatorcontrib>Sirivongs, Dhavee</creatorcontrib><creatorcontrib>Pahari, Dilip</creatorcontrib><creatorcontrib>Nath, Gokul</creatorcontrib><creatorcontrib>Ikizler, Talat Alp</creatorcontrib><title>A prospective, multi-centre, observational study to examine kidney disease progression in adults with chronic kidney disease - CKDOD - Study design and preliminary results</title><title>BMC nephrology</title><addtitle>BMC Nephrol</addtitle><description>The objective of this article is to describe the organisation of an international, clinical registry, the Chronic Kidney Disease Observational Database (CKDOD), the processes of enrolling patients and entering data and preliminary results to date.
The Chronic Kidney Disease Observational Database (CKDOD) is designed to assess the association between different factors with a known influence on chronic kidney disease (CKD) progression as well as treatment strategies such as dietary modifications, blood pressure control and pharmacological interventions in Asian countries (India, China, Malaysia and Thailand). The only inclusion criterion is the presence of CKD stage 2 or higher as defined by the KDIGO guidelines. Demographic and clinical information are collected by a standardised electronic questionnaire, available in English and Chinese. The data are transferred to the CKDOD database either by e-mail or via web access. All data are checked for consistency and missing values. Collection of data started in September 2011 and by April 2015, data on 1323 individual patients had been submitted. The mean age at inclusion was 57 ± 14 years, 67 % were male and 36 % were diabetic. The baseline estimated glomerular filtration rate was 26 ml/min/1.73 m(2). Of all enrolled patients, 324 (24 %) received ketoanalogue supplementation during at least one recorded visit.
The CKDOD is a very large and comprehensive data repository, currently focused in subjects recruited from Asia. The database is expected to provide important long-term information on CKD progression, nutritional and metabolic derangements that accompany CKD progression and treatment strategies to ameliorate progression and complications of CKD.
Clinical Trial Registry - India: CTRI/2012/06/002743 ; 25th July 2012.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adults</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Care and treatment</subject><subject>Chronic kidney failure</subject><subject>Complications and side effects</subject><subject>Databases, Factual</subject><subject>Development and progression</subject><subject>Disease Progression</subject><subject>Female</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Morbidity</subject><subject>Nephrology</subject><subject>Prospective Studies</subject><subject>Renal Insufficiency, Chronic - complications</subject><subject>Research Design</subject><subject>Risk factors</subject><subject>Study Protocol</subject><subject>Young Adult</subject><issn>1471-2369</issn><issn>1471-2369</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNptks1u1DAUhSNERUvhAdggS2xYkGLHjp1skEZTWioqdQGsLSe-mXFJ7MFOBuaZeEluOqW0FbIs_53z2b46WfaK0RPGKvk-saKqipyyEnvN8vJJdsSEYnnBZf303vwwe57SNaVMVYI-yw4LKWtZ8Poo-70gmxjSBtrRbeEdGaZ-dHkLfoy4Ck2CuDWjC970JI2T3ZExEPhlBueBfHfWw45Yl8AkmEGrCCmhmjhPjEVWIj_duCbtOgbv2seOnCw_n16d4vjlhm0huRU6vUUY9A5vMXFHEDqjXmQHnekTvLwdj7NvZx-_Lj_ll1fnF8vFZd6KWow5yE6IqitLU7IODG2sUtZ2XQ2KUUaLVjWS1rYsuClr0fBOUqoawwQVFVe25MfZhz13MzUD2JtimF5vohvwNToYpx-eeLfWq7DVQlaKlwoBb28BMfyYII16cKmFvjcewpQ0UyWTqqi4ROmbR9LrMEWs9qxStZRKCPFPtTI9aOe7gPe2M1QvBLJkrRhH1cl_VNgsDK4NHjqH-w8MbG9oMQIpQnf3R0b1nDC9T5jGhOk5YXouzuv7xblz_I0U_wPJN84s</recordid><startdate>20151222</startdate><enddate>20151222</enddate><creator>Shah, Bharat</creator><creator>Kirpalani, Ashok</creator><creator>Sunder, Sham</creator><creator>Gupta, Ashwani</creator><creator>Khanna, Umesh</creator><creator>Chafekar, Deodatta</creator><creator>Tan, Li Ping</creator><creator>Sirivongs, Dhavee</creator><creator>Pahari, Dilip</creator><creator>Nath, Gokul</creator><creator>Ikizler, Talat Alp</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20151222</creationdate><title>A prospective, multi-centre, observational study to examine kidney disease progression in adults with chronic kidney disease - CKDOD - Study design and preliminary results</title><author>Shah, Bharat ; 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The Chronic Kidney Disease Observational Database (CKDOD) is designed to assess the association between different factors with a known influence on chronic kidney disease (CKD) progression as well as treatment strategies such as dietary modifications, blood pressure control and pharmacological interventions in Asian countries (India, China, Malaysia and Thailand). The only inclusion criterion is the presence of CKD stage 2 or higher as defined by the KDIGO guidelines. Demographic and clinical information are collected by a standardised electronic questionnaire, available in English and Chinese. The data are transferred to the CKDOD database either by e-mail or via web access. All data are checked for consistency and missing values. Collection of data started in September 2011 and by April 2015, data on 1323 individual patients had been submitted. The mean age at inclusion was 57 ± 14 years, 67 % were male and 36 % were diabetic. The baseline estimated glomerular filtration rate was 26 ml/min/1.73 m(2). Of all enrolled patients, 324 (24 %) received ketoanalogue supplementation during at least one recorded visit.
The CKDOD is a very large and comprehensive data repository, currently focused in subjects recruited from Asia. The database is expected to provide important long-term information on CKD progression, nutritional and metabolic derangements that accompany CKD progression and treatment strategies to ameliorate progression and complications of CKD.
Clinical Trial Registry - India: CTRI/2012/06/002743 ; 25th July 2012.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>26696239</pmid><doi>10.1186/s12882-015-0191-5</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Adults Aged Aged, 80 and over Care and treatment Chronic kidney failure Complications and side effects Databases, Factual Development and progression Disease Progression Female Health aspects Humans Male Middle Aged Morbidity Nephrology Prospective Studies Renal Insufficiency, Chronic - complications Research Design Risk factors Study Protocol Young Adult |
title | A prospective, multi-centre, observational study to examine kidney disease progression in adults with chronic kidney disease - CKDOD - Study design and preliminary results |
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