Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats

Gastric ulcers are among the most common diseases affecting humans. This study aimed at investigating the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats. The mechanism by which honey exerts its antiulcer potential was elucidated. Four groups of rats were used...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2016-01, Vol.2016 (2016), p.1-10
Hauptverfasser:	Harakeh, Steve, Ali, Soad S., Abdel-dayem, Umama A., Abbas, Aymn T., El-Shitany, Nagla A., Almasaudi, Saad B., Al Jaouni, Soad K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Anti-inflammatory drugs Antioxidants Antioxidants - pharmacology Antioxidants - therapeutic use Blood Glucose - metabolism Catalase - metabolism Cholesterol - blood Cytokines Disease Models, Animal Drinking Behavior - drug effects Drug dosages Enzymes Ethanol Feeding Behavior - drug effects Flavonoids Glutathione - metabolism Glutathione Peroxidase - metabolism Glycoproteins - metabolism Honey Interleukin-1beta - blood Interleukin-6 - blood Interleukins Lipid peroxidation Lipids Male Malondialdehyde - metabolism Medical research Nitric oxide Nitric Oxide - metabolism Omeprazole Rats Research centers Rodents Staining and Labeling Stomach Ulcer - drug therapy Stomach Ulcer - pathology Studies Superoxide Superoxide Dismutase - metabolism Toxicology Triglycerides - blood Tumor Necrosis Factor-alpha - blood Tumor necrosis factor-TNF Ulcers Weight Gain - drug effects
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