Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan

In response to tissue injury, hyaluronan (HA) polymers are cleaved by host hyaluronidases, generating small fragments that ligate Toll-like receptors (TLRs) to elicit inflammatory responses. Pathogenic bacteria such as group B Streptococcus (GBS) express and secrete hyaluronidases as a mechanism for...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cell host & microbe 2015-12, Vol.18 (6), p.694-704
Hauptverfasser:	Kolar, Stacey L., Kyme, Pierre, Tseng, Ching Wen, Soliman, Antoine, Kaplan, Amber, Liang, Jiurong, Nizet, Victor, Jiang, Dianhua, Murali, Ramachandran, Arditi, Moshe, Underhill, David M., Liu, George Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Disaccharides - metabolism Hyaluronic Acid - metabolism Hyaluronoglucosaminidase - metabolism Hydrolysis Immune Evasion Streptococcus agalactiae - enzymology Streptococcus agalactiae - immunology Streptococcus agalactiae - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!