Dysbiosis of upper respiratory tract microbiota in elderly pneumonia patients

Bacterial pneumonia is a major cause of morbidity and mortality in elderly. We hypothesize that dysbiosis between regular residents of the upper respiratory tract (URT) microbiome, that is balance between commensals and potential pathogens, is involved in pathogen overgrowth and consequently disease...

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Veröffentlicht in:	The ISME Journal 2016-01, Vol.10 (1), p.97-108
Hauptverfasser:	de Steenhuijsen Piters, Wouter A A, Huijskens, Elisabeth G W, Wyllie, Anne L, Biesbroek, Giske, van den Bergh, Menno R, Veenhoven, Reinier H, Wang, Xinhui, Trzciński, Krzysztof, Bonten, Marc J, Rossen, John W A, Sanders, Elisabeth A M, Bogaert, Debby
Format:	Artikel
Sprache:	eng
Schlagworte:	45/22 45/23 45/77 631/158/855 631/326/2565/2134 692/420 692/699/255/1318 Aged Aged, 80 and over Anaerobic bacteria Bacteria - genetics Bacteria - isolation & purification Bacterial Infections - microbiology Biomedical and Life Sciences Case-Control Studies Dysbiosis - microbiology Ecology Evolutionary Biology Female Humans Lactobacillus Leptotrichia Life Sciences Male Microbial Ecology Microbial Genetics and Genomics Microbiology Microbiota Original original-article Oropharynx - microbiology Pathogens Pneumonia - microbiology Prevotella melaninogenica Relative abundance Respiratory tract RNA, Ribosomal, 16S - genetics Streptococcus Veillonella Young adults
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