Genomic Characterization of Poorly Differentiated Neuroendocrine Carcinoma in a Pediatric Patient

Primary neuroendocrine carcinomas (NEC) are rare tumors in children and young adults, resulting in a lack of standardized treatment approach. To refine the molecular taxonomy of these rare tumors, we performed whole exome sequencing in a pediatric patient with mediastinal NEC. We identified a somati...

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Veröffentlicht in:	Journal of pediatric hematology/oncology 2016-01, Vol.38 (1), p.e21-e25
Hauptverfasser:	Bhatla, Teena, Dandekar, Smita, Lu, Benjamin Y, Wang, Jinhua, Han, Eugenia, Bitterman, Danielle, Jones, Courtney L, Evensen, Nikki A, Magid, Margret, Meyer, Julia A, Carroll, William L
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Neuroendocrine - genetics Child, Preschool DNA Mutational Analysis Female Genome, Human Humans Mediastinal Neoplasms - genetics Reverse Transcriptase Polymerase Chain Reaction
Online-Zugang:	Volltext
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